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- W2067720792 abstract "THE third component of complement (C3) is critically involved in host defense and the maintenance of normal immunologic homeostasis.1 , 2 It is a central component of both the classical and alternative pathways of complement, and its major cleavage product, C3b, serves as an important serum opsonin.1 , 2 Another cleavage product, C3a, is a potent anaphylatoxin that is thought to be important in the initiation of local inflammatory processes.1 , 2 Therefore, attention has focused on infection as the major clinical problem in the rare patients with congenital C3 deficiency3 4 5 6 7 or marked C3 consumption.8 , 9 In the present report, we describe a patient with a congenital . . ." @default.
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- W2067720792 date "1983-04-28" @default.
- W2067720792 modified "2023-09-26" @default.
- W2067720792 title "Circulating Immune Complexes and Glomerulonephritis in a Patient with Congenital Absence of the Third Component of Complement" @default.
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- W2067720792 doi "https://doi.org/10.1056/nejm198304283081706" @default.
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