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• W2067771497 abstract "Chronic idiopathic singultus (hiccup) is a debilitating condition affecting mostly elderly males. While in the past, pharmacologic singultus treatment was mostly “trial and error,” more recently, treatment has become both more evidence based and pathophysiology guided. A combination of an acidity-reducing drug (H2-receptor blocker or proton pump inhibitor) with baclofen (gamma-amino-butyric-acid receptor type B agonist) has become the most widely used regimen. Some clinicians replace or supplement baclofen with gabapentin. We present three cases of chronic idiopathic hiccup managed with gabapentin or another alpha-2-delta ligand, pregabalin. This is the first reported use of pregabalin for this indication." @default.
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• W2067771497 date "2007-06-01" @default.
• W2067771497 modified "2023-09-25" @default.
• W2067771497 title "Alpha-2-Delta Ligands for Singultus (Hiccup) Treatment: Three Case Reports" @default.
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• W2067771497 doi "https://doi.org/10.1016/j.jpainsymman.2006.09.026" @default.
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