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• W2067807592 abstract "All lepidopteran baculovirus genomes sequenced encode a homolog of the Bombyx mori nucleopolyhedrovirus orf61 gene (Bm61). To determine the role of Bm61 in the baculoviral life cycle, we constructed a Bm61 knockout virus and characterized it in cells. We observed that the Bm61 deletion bacmid led to a defect in production of infectious budded virus (BV). Quantitative PCR analysis of BV in the media culturing the transfected cell indicated that BV was not produced due to Bm61 deletion. Electron microscope analysis showed that in the knockout of Bm61, nucleocapsids were not transported from the nucleus to the cytoplasm. From these results we concluded that BM61 is required in the BV pathway for the egress of nucleocapsids from the nucleus to the cytoplasm." @default.
• W2067807592 created "2016-06-24" @default.
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• W2067807592 date "2012-03-02" @default.
• W2067807592 modified "2023-10-16" @default.
• W2067807592 title "BM61 of <i>Bombyx mori</i> nucleopolyhedrovirus: Its involvement in the egress of nucleocapsids from the nucleus" @default.
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• W2067807592 doi "https://doi.org/10.1016/j.febslet.2011.12.040" @default.
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