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- W2067848327 abstract "Background: HIV disease progression in infants and children is rapid compare to adults. This picture is gloomier in sub Sahara Africa due to the co-morbidities of malaria, diarrhea disease and malnutrition. Therefore, the goal of treatment and care of the HIV infected child is to promote health and prevent disease progression. This present study evaluates immunologic recovery after one year of antiretroviral therapy using CD 4 cells counts. Aims and Objectives: To determine the pattern of CD4 count rise after one year of Zodovudine base first line therapy in HIV infected children. Method: HIV infected children who were treatment naïve and commenced on Zodovudine based regimen were enrolled into the study. Age, weight, CD4 counts and Hematocrit prior to initiation of treatment were all recorded and entered into a proforma. These parameters were reassessed again at 6 and 12 months on treatment and recorded. Data collected was analyzed using SPSS version 12 and presented as means and standard deviation. Results: A total of 92 HIV infected children completed the study, of which 48 were males and 44 females. Mean age at initiation of therapy was 5.4years while mean baseline Cd4 counts was 688 cell/mm. mean CD4 counts at 12 months was 746 cells, gain in CD4 among subjects was found to be statistically significant. (P < 0.001) Conclusions: There is significant increase in the Cd4 count after one year of treatment but no significant change in weight and hematocrit." @default.
- W2067848327 created "2016-06-24" @default.
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- W2067848327 date "2009-06-01" @default.
- W2067848327 modified "2023-10-17" @default.
- W2067848327 title "264 Immunologic recovery among HIV infected children on first line antiretroviral therapy in Kano, Nigeria" @default.
- W2067848327 doi "https://doi.org/10.1097/01.qai.0000351219.23294.a5" @default.
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