FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067864160> ?p ?o ?g. }

• W2067864160 endingPage "665" @default.
• W2067864160 startingPage "660" @default.
• W2067864160 abstract "Immunoliposomes were prepared by conjugating anti-carcinoembryonic antigen (CEA) monoclonal antibody with liposomes containing [10B]compound. These immunoliposomes were shown to bind selectively to human pancreatic carcinoma cells (AsPC-1) bearing CEA on their surface. The cytotoxic effects of locally injected [10B]compound, multilamellar liposomes containing [10B]compound or [10B]immunoliposomes (anti-CEA) on human pancreatic carcinoma xenografts in nude mice were evaluated with thermal neutron irradiation. After thermal neutron irradiation of mice injected with [10B]solution, 10B-containing liposomes or [10B]immunoliposomes, AsPC-1 tumour growth was suppressed relative to controls. Injection of [10B]immunoliposomes caused the greatest tumour suppression with thermal neutron irradiation in vivo. Histopathologically, hyalinization and necrosis were found in 10B-treated tumours, while tumour tissue injected with saline or saline-containing immunoliposomes showed neither destruction nor necrosis. These results suggest that intratumoral injection of boronated immunoliposomes can increase the retention of 10B atoms by tumour cells, causing tumour growth suppression in vivo upon thermal neutron irradiation. Boron neutron capture therapy (BNCT) with intratumoral injection of immunoliposomes is able to destroy malignant cells in the marginal portion between normal tissues and cancer tissues from the side of 4He generation." @default.
• W2067864160 created "2016-06-24" @default.
• W2067864160 creator A5004836767 @default.
• W2067864160 creator A5010421140 @default.
• W2067864160 creator A5018287874 @default.
• W2067864160 creator A5035373444 @default.
• W2067864160 creator A5052095739 @default.
• W2067864160 creator A5063644364 @default.
• W2067864160 creator A5069201854 @default.
• W2067864160 creator A5089429184 @default.
• W2067864160 creator A5090216578 @default.
• W2067864160 creator A5090278217 @default.
• W2067864160 date "1997-03-01" @default.
• W2067864160 modified "2023-10-06" @default.
• W2067864160 title "Inhibition of human pancreatic cancer growth in nude mice by boron neutron capture therapy" @default.
• W2067864160 cites W1961663552 @default.
• W2067864160 cites W1968162053 @default.
• W2067864160 cites W1968852429 @default.
• W2067864160 cites W1977934288 @default.
• W2067864160 cites W1984622940 @default.
• W2067864160 cites W1992133515 @default.
• W2067864160 cites W2004102690 @default.
• W2067864160 cites W2009038500 @default.
• W2067864160 cites W2018925122 @default.
• W2067864160 cites W2022784273 @default.
• W2067864160 cites W2059589933 @default.
• W2067864160 cites W2068009234 @default.
• W2067864160 cites W2077670319 @default.
• W2067864160 cites W2096106209 @default.
• W2067864160 cites W2101904127 @default.
• W2067864160 cites W2105834661 @default.
• W2067864160 cites W2105994185 @default.
• W2067864160 cites W2116301180 @default.
• W2067864160 cites W2164933324 @default.
• W2067864160 cites W2166458266 @default.
• W2067864160 cites W2169095898 @default.
• W2067864160 cites W2427929070 @default.
• W2067864160 doi "https://doi.org/10.1038/bjc.1997.118" @default.
• W2067864160 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2063329" @default.
• W2067864160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9043021" @default.
• W2067864160 hasPublicationYear "1997" @default.
• W2067864160 type Work @default.
• W2067864160 sameAs 2067864160 @default.
• W2067864160 citedByCount "67" @default.
• W2067864160 countsByYear W20678641602012 @default.
• W2067864160 countsByYear W20678641602013 @default.
• W2067864160 countsByYear W20678641602014 @default.
• W2067864160 countsByYear W20678641602015 @default.
• W2067864160 countsByYear W20678641602016 @default.
• W2067864160 countsByYear W20678641602017 @default.
• W2067864160 countsByYear W20678641602018 @default.
• W2067864160 countsByYear W20678641602019 @default.
• W2067864160 countsByYear W20678641602020 @default.
• W2067864160 countsByYear W20678641602021 @default.
• W2067864160 countsByYear W20678641602022 @default.
• W2067864160 crossrefType "journal-article" @default.
• W2067864160 hasAuthorship W2067864160A5004836767 @default.
• W2067864160 hasAuthorship W2067864160A5010421140 @default.
• W2067864160 hasAuthorship W2067864160A5018287874 @default.
• W2067864160 hasAuthorship W2067864160A5035373444 @default.
• W2067864160 hasAuthorship W2067864160A5052095739 @default.
• W2067864160 hasAuthorship W2067864160A5063644364 @default.
• W2067864160 hasAuthorship W2067864160A5069201854 @default.
• W2067864160 hasAuthorship W2067864160A5089429184 @default.
• W2067864160 hasAuthorship W2067864160A5090216578 @default.
• W2067864160 hasAuthorship W2067864160A5090278217 @default.
• W2067864160 hasBestOaLocation W20678641601 @default.
• W2067864160 hasConcept C121608353 @default.
• W2067864160 hasConcept C126322002 @default.
• W2067864160 hasConcept C142724271 @default.
• W2067864160 hasConcept C150903083 @default.
• W2067864160 hasConcept C153911025 @default.
• W2067864160 hasConcept C159654299 @default.
• W2067864160 hasConcept C185154212 @default.
• W2067864160 hasConcept C185592680 @default.
• W2067864160 hasConcept C203014093 @default.
• W2067864160 hasConcept C207001950 @default.
• W2067864160 hasConcept C2780210213 @default.
• W2067864160 hasConcept C502942594 @default.
• W2067864160 hasConcept C503630168 @default.
• W2067864160 hasConcept C542903549 @default.
• W2067864160 hasConcept C55493867 @default.
• W2067864160 hasConcept C71924100 @default.
• W2067864160 hasConcept C86803240 @default.
• W2067864160 hasConceptScore W2067864160C121608353 @default.
• W2067864160 hasConceptScore W2067864160C126322002 @default.
• W2067864160 hasConceptScore W2067864160C142724271 @default.
• W2067864160 hasConceptScore W2067864160C150903083 @default.
• W2067864160 hasConceptScore W2067864160C153911025 @default.
• W2067864160 hasConceptScore W2067864160C159654299 @default.
• W2067864160 hasConceptScore W2067864160C185154212 @default.
• W2067864160 hasConceptScore W2067864160C185592680 @default.
• W2067864160 hasConceptScore W2067864160C203014093 @default.
• W2067864160 hasConceptScore W2067864160C207001950 @default.
• W2067864160 hasConceptScore W2067864160C2780210213 @default.
• W2067864160 hasConceptScore W2067864160C502942594 @default.
• W2067864160 hasConceptScore W2067864160C503630168 @default.
• W2067864160 hasConceptScore W2067864160C542903549 @default.

• next