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• W2067874999 abstract "Thyrotropin-releasing hormone (TRH) is expressed at early postmitotic stages of hypothalamic neuron development, in the mouse and rat, as revealed by the presence of the mature peptide, of pro-TRH mRNAs, and of large precursor forms. This indicates a coordinate expression of several genes encoding, respectively, pro-TRH, its processing enzymes, and the cell machinery for intracellular transport, sorting, and release of TRH. During development, an acceleration of pro-TRH processing is revealed by an increased proportion of the mature peptide. This is correlated with changes in the respective distribution of pro-TRH and TRH along neurites and the ontogenesis of neurosecretory granules." @default.
• W2067874999 created "2016-06-24" @default.
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• W2067874999 date "1992-03-01" @default.
• W2067874999 modified "2023-09-24" @default.
• W2067874999 title "Ontogeny of thyrotropin-releasing hormone biosynthesis and release in hypothalamic neurons" @default.
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• W2067874999 doi "https://doi.org/10.1016/1043-2760(92)90045-3" @default.
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