FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067893090> ?p ?o ?g. }

• W2067893090 endingPage "20" @default.
• W2067893090 startingPage "11" @default.
• W2067893090 abstract "Brain metastases are a common and devastating complication in patients with malignant melanoma. Therapeutic options for these patients are limited, and the prognosis is usually poor. Object. A retrospective review of 6953 patients with melanoma treated at a single institution was undertaken to identify demographic factors associated with the development of clinically significant brain metastases in 702 of these patients and to determine the factors influencing the prognosis of this population to permit more informed recommendations regarding surgical therapy. Methods. Factors found to be associated with the development of brain metastases included male gender, primary lesions located on mucosal surfaces or on the skin of the trunk or head and neck, thick or ulcerated primary lesions, and histological findings of acral lentiginous or nodular lesions. The overall median survival time of all patients with brain metastases was 113.2 days, and these metastases contributed to the death of 94.5% of the patients in this group. Patients with primary lesions located in the head or neck region had a significantly shorter survival time relative to other patients with brain metastases, whereas patients with a single brain metastasis, patients without lung or multiple other visceral metastases, and patients whose initial presentation with melanoma included a brain metastasis had a significantly better prognosis. The small group of patients who survived for more than 3 years was characterized by the presence of a surgically treated, single brain metastasis in the absence of other visceral metastatic disease. Conclusions. Although most patients with brain metastases resulting from melanoma have a dismal prognosis, some who are likely to survive for longer periods can be identified. In these patients surgical resection can significantly prolong meaningful survival. The decision to recommend surgery should be based primarily on the resectability of the brain metastases and on the status and number of other organs with metastatic lesions." @default.
• W2067893090 created "2016-06-24" @default.
• W2067893090 creator A5037596103 @default.
• W2067893090 creator A5056225827 @default.
• W2067893090 creator A5083472710 @default.
• W2067893090 creator A5090923288 @default.
• W2067893090 date "1998-01-01" @default.
• W2067893090 modified "2023-09-23" @default.
• W2067893090 title "Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma" @default.
• W2067893090 cites W1215086530 @default.
• W2067893090 cites W1759766614 @default.
• W2067893090 cites W1965848963 @default.
• W2067893090 cites W1965911653 @default.
• W2067893090 cites W1970049405 @default.
• W2067893090 cites W1977581065 @default.
• W2067893090 cites W1978113416 @default.
• W2067893090 cites W1979241308 @default.
• W2067893090 cites W1981472724 @default.
• W2067893090 cites W1982379973 @default.
• W2067893090 cites W1982525021 @default.
• W2067893090 cites W1989683871 @default.
• W2067893090 cites W1996078409 @default.
• W2067893090 cites W2003867245 @default.
• W2067893090 cites W2005612119 @default.
• W2067893090 cites W2007323618 @default.
• W2067893090 cites W2007872707 @default.
• W2067893090 cites W2020477396 @default.
• W2067893090 cites W2021339716 @default.
• W2067893090 cites W2023506394 @default.
• W2067893090 cites W2025021612 @default.
• W2067893090 cites W2031616920 @default.
• W2067893090 cites W2032768995 @default.
• W2067893090 cites W2034690966 @default.
• W2067893090 cites W2041226919 @default.
• W2067893090 cites W2042155374 @default.
• W2067893090 cites W2044010200 @default.
• W2067893090 cites W2045394208 @default.
• W2067893090 cites W2046301517 @default.
• W2067893090 cites W2049525098 @default.
• W2067893090 cites W2059681875 @default.
• W2067893090 cites W2062247475 @default.
• W2067893090 cites W2063058537 @default.
• W2067893090 cites W2063384276 @default.
• W2067893090 cites W2064957047 @default.
• W2067893090 cites W2065626916 @default.
• W2067893090 cites W2067860877 @default.
• W2067893090 cites W2070837465 @default.
• W2067893090 cites W2073760043 @default.
• W2067893090 cites W2076368332 @default.
• W2067893090 cites W2078045193 @default.
• W2067893090 cites W2078723281 @default.
• W2067893090 cites W2084487554 @default.
• W2067893090 cites W2086514113 @default.
• W2067893090 cites W2093856946 @default.
• W2067893090 cites W2094077137 @default.
• W2067893090 cites W2098807286 @default.
• W2067893090 cites W2110342012 @default.
• W2067893090 cites W2112898381 @default.
• W2067893090 cites W2117500200 @default.
• W2067893090 cites W2131646514 @default.
• W2067893090 cites W2133031595 @default.
• W2067893090 cites W2140585508 @default.
• W2067893090 cites W2142741704 @default.
• W2067893090 cites W2187668060 @default.
• W2067893090 cites W2216821117 @default.
• W2067893090 cites W2329793926 @default.
• W2067893090 cites W2410037813 @default.
• W2067893090 cites W3041047318 @default.
• W2067893090 cites W4213377140 @default.
• W2067893090 cites W4239639001 @default.
• W2067893090 cites W4247085137 @default.
• W2067893090 cites W8282282 @default.
• W2067893090 cites W1993905871 @default.
• W2067893090 doi "https://doi.org/10.3171/jns.1998.88.1.0011" @default.
• W2067893090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9420067" @default.
• W2067893090 hasPublicationYear "1998" @default.
• W2067893090 type Work @default.
• W2067893090 sameAs 2067893090 @default.
• W2067893090 citedByCount "478" @default.
• W2067893090 countsByYear W20678930902012 @default.
• W2067893090 countsByYear W20678930902013 @default.
• W2067893090 countsByYear W20678930902014 @default.
• W2067893090 countsByYear W20678930902015 @default.
• W2067893090 countsByYear W20678930902016 @default.
• W2067893090 countsByYear W20678930902017 @default.
• W2067893090 countsByYear W20678930902018 @default.
• W2067893090 countsByYear W20678930902019 @default.
• W2067893090 countsByYear W20678930902020 @default.
• W2067893090 countsByYear W20678930902021 @default.
• W2067893090 countsByYear W20678930902022 @default.
• W2067893090 countsByYear W20678930902023 @default.
• W2067893090 crossrefType "journal-article" @default.
• W2067893090 hasAuthorship W2067893090A5037596103 @default.
• W2067893090 hasAuthorship W2067893090A5056225827 @default.
• W2067893090 hasAuthorship W2067893090A5083472710 @default.
• W2067893090 hasAuthorship W2067893090A5090923288 @default.
• W2067893090 hasConcept C121608353 @default.
• W2067893090 hasConcept C126322002 @default.

• next