FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067939115> ?p ?o ?g. }

• W2067939115 abstract "The introduction of the endosymbiotic bacterium, Wolbachia into Aedes aegypti populations is a novel approach to reduce disease transmission. The presence of Wolbachia limits the ability of the mosquito to transmit dengue virus (DENV) and the strength of this effect appears to correlate with Wolbachia densities in the mosquito. There is also some evidence that Wolbachia densities may increase following the consumption of a bloodmeal. Here we have examined whether multiple blood feeds lead to increases in density or associated changes in Wolbachia-mediated blocking of DENV. The Wolbachia infected Aedes aegypti mosquito line was used for the study. There were three treatment groups; a non-blood fed control, a second group fed once and a third group fed twice on human blood. All groups were orally infected with DENV-2 and then their midguts and salivary glands were dissected 10–11 days post infection. RNA/DNA was simultaneously extracted from each tissue and subsequently used for DENV RNA copies and Wolbachia density quantification, respectively. We found variation between replicate vector competence experiments and no clear evidence that Wolbachia numbers increased in either the salivary glands or remainder of the body with feeding and hence saw no corresponding improvements in DENV blocking. Aedes aegypti are “sip” feeders returning often to obtain bloodmeals and hence it is important to assess whether repeat blood feeding improved the efficacy of Wolbachia-based DENV blocking. Our work suggests in the laboratory context when Wolbachia densities are high that repeat feeding does not improve blocking and hence this ability should likely be stable with respect to feeding cycle in the field." @default.
• W2067939115 created "2016-06-24" @default.
• W2067939115 creator A5042707005 @default.
• W2067939115 creator A5062848617 @default.
• W2067939115 creator A5081582718 @default.
• W2067939115 date "2015-04-24" @default.
• W2067939115 modified "2023-10-14" @default.
• W2067939115 title "Effect of repeat human blood feeding on Wolbachia density and dengue virus infection in Aedes aegypti" @default.
• W2067939115 cites W1963710629 @default.
• W2067939115 cites W1972541583 @default.
• W2067939115 cites W2001401225 @default.
• W2067939115 cites W2009246694 @default.
• W2067939115 cites W2010188273 @default.
• W2067939115 cites W2011148871 @default.
• W2067939115 cites W2017207494 @default.
• W2067939115 cites W2017971345 @default.
• W2067939115 cites W2025492442 @default.
• W2067939115 cites W2028475773 @default.
• W2067939115 cites W2029234361 @default.
• W2067939115 cites W2030942380 @default.
• W2067939115 cites W2032791847 @default.
• W2067939115 cites W2036898301 @default.
• W2067939115 cites W2036933537 @default.
• W2067939115 cites W2054149375 @default.
• W2067939115 cites W2056614797 @default.
• W2067939115 cites W2065557730 @default.
• W2067939115 cites W2069937826 @default.
• W2067939115 cites W2070532728 @default.
• W2067939115 cites W2074576583 @default.
• W2067939115 cites W2081051813 @default.
• W2067939115 cites W2090199520 @default.
• W2067939115 cites W2092133388 @default.
• W2067939115 cites W2096383776 @default.
• W2067939115 cites W2097154739 @default.
• W2067939115 cites W2106143798 @default.
• W2067939115 cites W2116127013 @default.
• W2067939115 cites W2124469739 @default.
• W2067939115 cites W2131222241 @default.
• W2067939115 cites W2133250947 @default.
• W2067939115 cites W2144775280 @default.
• W2067939115 cites W2146758165 @default.
• W2067939115 cites W2147402521 @default.
• W2067939115 cites W2149671007 @default.
• W2067939115 cites W2151688421 @default.
• W2067939115 cites W2161519868 @default.
• W2067939115 cites W2175397736 @default.
• W2067939115 cites W2181243794 @default.
• W2067939115 cites W2330277578 @default.
• W2067939115 cites W4234341049 @default.
• W2067939115 doi "https://doi.org/10.1186/s13071-015-0853-y" @default.
• W2067939115 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4413987" @default.
• W2067939115 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25903749" @default.
• W2067939115 hasPublicationYear "2015" @default.
• W2067939115 type Work @default.
• W2067939115 sameAs 2067939115 @default.
• W2067939115 citedByCount "15" @default.
• W2067939115 countsByYear W20679391152016 @default.
• W2067939115 countsByYear W20679391152017 @default.
• W2067939115 countsByYear W20679391152018 @default.
• W2067939115 countsByYear W20679391152019 @default.
• W2067939115 countsByYear W20679391152020 @default.
• W2067939115 countsByYear W20679391152021 @default.
• W2067939115 countsByYear W20679391152022 @default.
• W2067939115 countsByYear W20679391152023 @default.
• W2067939115 crossrefType "journal-article" @default.
• W2067939115 hasAuthorship W2067939115A5042707005 @default.
• W2067939115 hasAuthorship W2067939115A5062848617 @default.
• W2067939115 hasAuthorship W2067939115A5081582718 @default.
• W2067939115 hasBestOaLocation W20679391151 @default.
• W2067939115 hasConcept C104317684 @default.
• W2067939115 hasConcept C126831891 @default.
• W2067939115 hasConcept C151730666 @default.
• W2067939115 hasConcept C159047783 @default.
• W2067939115 hasConcept C173758957 @default.
• W2067939115 hasConcept C18903297 @default.
• W2067939115 hasConcept C2522874641 @default.
• W2067939115 hasConcept C2777775583 @default.
• W2067939115 hasConcept C2779343474 @default.
• W2067939115 hasConcept C2779356413 @default.
• W2067939115 hasConcept C2779635636 @default.
• W2067939115 hasConcept C2780688631 @default.
• W2067939115 hasConcept C40767141 @default.
• W2067939115 hasConcept C533803919 @default.
• W2067939115 hasConcept C54355233 @default.
• W2067939115 hasConcept C86803240 @default.
• W2067939115 hasConcept C90856448 @default.
• W2067939115 hasConcept C92087593 @default.
• W2067939115 hasConceptScore W2067939115C104317684 @default.
• W2067939115 hasConceptScore W2067939115C126831891 @default.
• W2067939115 hasConceptScore W2067939115C151730666 @default.
• W2067939115 hasConceptScore W2067939115C159047783 @default.
• W2067939115 hasConceptScore W2067939115C173758957 @default.
• W2067939115 hasConceptScore W2067939115C18903297 @default.
• W2067939115 hasConceptScore W2067939115C2522874641 @default.
• W2067939115 hasConceptScore W2067939115C2777775583 @default.
• W2067939115 hasConceptScore W2067939115C2779343474 @default.
• W2067939115 hasConceptScore W2067939115C2779356413 @default.
• W2067939115 hasConceptScore W2067939115C2779635636 @default.
• W2067939115 hasConceptScore W2067939115C2780688631 @default.
• W2067939115 hasConceptScore W2067939115C40767141 @default.

• next