FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067945088> ?p ?o ?g. }

• W2067945088 endingPage "124" @default.
• W2067945088 startingPage "124" @default.
• W2067945088 abstract "• We tested the concept that estrogen directly stimulates growth hormone (GH) production by determining whether low-dose treatment with ethinyl estradiol increases the GH reserve, as assessed by levodopa administration, without inhibiting somatomedin-C (Sm-C) levels. Twenty-three prepubertal short normal children underwent levodopa tests before and after being treated with ethinyl estradiol. One bedtime dose of ethinyl estradiol (20 to 40 μg/sq m, n = 8) resulted in a significant increase in GH levels during levodopa testing, with no significant change in Sm-C levels (0.27±0.03 vs 0.36±0.1 units/mL). Two days of a comparable ethinyl estradiol dose (n=12) raised the mean basal GH level (2.4±0.4 vs 9±3 ng/mL) and had a similar effect on peak GH response, without affecting the mean Sm-C level. Eighteen of the 23 patients responded (maximum GH level, ≥7 ng/mL) to levodopa before estrogen; all 20 children who received ethinyl estradiol priming in a dose of 20 μg/sq m or more also responded. We conclude that low-dose estrogen therapy rapidly stimulates GH production without decreasing Sm-C plasma levels. These results support the concept that the estrogen effect is direct. This action may be important for the stimulation of growth by estrogen. This effect can be conveniently employed to enhance the specificity of the levodopa test for profound GH deficiency. (<i>AJDC</i>1986;140:124-127)" @default.
• W2067945088 created "2016-06-24" @default.
• W2067945088 creator A5006387457 @default.
• W2067945088 creator A5045328254 @default.
• W2067945088 creator A5089081199 @default.
• W2067945088 date "1986-02-01" @default.
• W2067945088 modified "2023-09-25" @default.
• W2067945088 title "Administration of Low-Dose Estrogen Rapidly and Directly Stimulates Growth Hormone Production" @default.
• W2067945088 cites W1520106087 @default.
• W2067945088 cites W1565870791 @default.
• W2067945088 cites W1897112047 @default.
• W2067945088 cites W1966856476 @default.
• W2067945088 cites W1972083618 @default.
• W2067945088 cites W1974735348 @default.
• W2067945088 cites W1979765112 @default.
• W2067945088 cites W1981581994 @default.
• W2067945088 cites W1983114054 @default.
• W2067945088 cites W1997993870 @default.
• W2067945088 cites W2001761779 @default.
• W2067945088 cites W2002292851 @default.
• W2067945088 cites W2012937602 @default.
• W2067945088 cites W2043089512 @default.
• W2067945088 cites W2046261325 @default.
• W2067945088 cites W2049144714 @default.
• W2067945088 cites W2069741555 @default.
• W2067945088 cites W2087432811 @default.
• W2067945088 cites W2092519572 @default.
• W2067945088 cites W2095296676 @default.
• W2067945088 cites W2097551860 @default.
• W2067945088 cites W2169916499 @default.
• W2067945088 cites W2798643531 @default.
• W2067945088 cites W2073125089 @default.
• W2067945088 doi "https://doi.org/10.1001/archpedi.1986.02140160042027" @default.
• W2067945088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3946321" @default.
• W2067945088 hasPublicationYear "1986" @default.
• W2067945088 type Work @default.
• W2067945088 sameAs 2067945088 @default.
• W2067945088 citedByCount "46" @default.
• W2067945088 countsByYear W20679450882012 @default.
• W2067945088 countsByYear W20679450882013 @default.
• W2067945088 countsByYear W20679450882014 @default.
• W2067945088 countsByYear W20679450882015 @default.
• W2067945088 countsByYear W20679450882017 @default.
• W2067945088 countsByYear W20679450882018 @default.
• W2067945088 countsByYear W20679450882019 @default.
• W2067945088 countsByYear W20679450882021 @default.
• W2067945088 countsByYear W20679450882022 @default.
• W2067945088 crossrefType "journal-article" @default.
• W2067945088 hasAuthorship W2067945088A5006387457 @default.
• W2067945088 hasAuthorship W2067945088A5045328254 @default.
• W2067945088 hasAuthorship W2067945088A5089081199 @default.
• W2067945088 hasConcept C126322002 @default.
• W2067945088 hasConcept C134018914 @default.
• W2067945088 hasConcept C24998067 @default.
• W2067945088 hasConcept C2777164284 @default.
• W2067945088 hasConcept C2777956591 @default.
• W2067945088 hasConcept C2778024521 @default.
• W2067945088 hasConcept C2778537899 @default.
• W2067945088 hasConcept C2779134260 @default.
• W2067945088 hasConcept C2779306644 @default.
• W2067945088 hasConcept C2779734285 @default.
• W2067945088 hasConcept C2780304432 @default.
• W2067945088 hasConcept C2908647359 @default.
• W2067945088 hasConcept C2986817661 @default.
• W2067945088 hasConcept C71315377 @default.
• W2067945088 hasConcept C71924100 @default.
• W2067945088 hasConcept C99454951 @default.
• W2067945088 hasConceptScore W2067945088C126322002 @default.
• W2067945088 hasConceptScore W2067945088C134018914 @default.
• W2067945088 hasConceptScore W2067945088C24998067 @default.
• W2067945088 hasConceptScore W2067945088C2777164284 @default.
• W2067945088 hasConceptScore W2067945088C2777956591 @default.
• W2067945088 hasConceptScore W2067945088C2778024521 @default.
• W2067945088 hasConceptScore W2067945088C2778537899 @default.
• W2067945088 hasConceptScore W2067945088C2779134260 @default.
• W2067945088 hasConceptScore W2067945088C2779306644 @default.
• W2067945088 hasConceptScore W2067945088C2779734285 @default.
• W2067945088 hasConceptScore W2067945088C2780304432 @default.
• W2067945088 hasConceptScore W2067945088C2908647359 @default.
• W2067945088 hasConceptScore W2067945088C2986817661 @default.
• W2067945088 hasConceptScore W2067945088C71315377 @default.
• W2067945088 hasConceptScore W2067945088C71924100 @default.
• W2067945088 hasConceptScore W2067945088C99454951 @default.
• W2067945088 hasIssue "2" @default.
• W2067945088 hasLocation W20679450881 @default.
• W2067945088 hasLocation W20679450882 @default.
• W2067945088 hasOpenAccess W2067945088 @default.
• W2067945088 hasPrimaryLocation W20679450881 @default.
• W2067945088 hasRelatedWork W1995647897 @default.
• W2067945088 hasRelatedWork W2013481652 @default.
• W2067945088 hasRelatedWork W2054992011 @default.
• W2067945088 hasRelatedWork W2064416809 @default.
• W2067945088 hasRelatedWork W2077325982 @default.
• W2067945088 hasRelatedWork W2108578925 @default.
• W2067945088 hasRelatedWork W2109882125 @default.
• W2067945088 hasRelatedWork W2118001750 @default.
• W2067945088 hasRelatedWork W2168803779 @default.
• W2067945088 hasRelatedWork W4245320514 @default.

• next