FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067951904> ?p ?o ?g. }

• W2067951904 endingPage "47" @default.
• W2067951904 startingPage "38" @default.
• W2067951904 abstract "The objective of this study was to determine whether the simultaneous measurement of tissue pH, pCO(2), and pO(2) with a multiple-parameter fiberoptic sensor (Paratrend 7) can be used for continuous monitoring of hepatic microperfusion in a pig model of hepatic ischemia given endothelin(A) receptor antagonist (ET(A)-RA) or isotonic saline.Fourteen anesthetized swine were subjected to 2 h of hepatic vascular exclusion. The animals were randomized into two groups: control group (n = 7, saline solution iv) and therapy group (n = 7, ET(A)-RA). For evaluation of ischemia-reperfusion injury, the data of the multiple-parameter sensor (pO(2para), pCO(2para), and pH(para)) were compared with partial oxygen pressure in tissue (p(ti)O(2)), laser Doppler flow, and systemic hemodynamic, metabolic data, and time course of transaminases.In the control group 30 and 60 min after reperfusion, the following values were measured: p(ti)O(2): 34.0 +/- 8.6 / 36.3 +/- 7.0 mm Hg (P < 0.05 vs. preop.: 49.8 +/- 12.1 mm Hg), laser Doppler area: 133.3 +/- 23.2 / 156.4 +/- 15.4 (P < 0.05 vs. preop.: 215.9 +/- 14.8). Animals in the therapy group revealed significantly improved values (p(ti)O(2): 54.0 +/- 8.6 / 58.1 +/- 7.8 mm Hg, laser Doppler: 210.2 +/- 38.5 / 225.2 +/- 21.3; P < 0.05). Using the Paratrend, also an improvement in the therapy group was seen 30 and 60 min after reperfusion. The values showed a strong correlation with p(ti)O(2) (r = 0.895; P < 0.05) and laser Doppler flow (r = 0.807; P < 0.05). In the treatment group, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and glutamate dehydrogenase (GLDH) were reduced 6 and 18 h after reperfusion, respectively, indicating hepatoprotection by the therapy (P < 0.05 vs. control).The Paratrend sensor offers the opportunity to study postischemic organ hemodynamics through the simultaneous measurement of interstitial pH, pCO(2), and pO(2) in a small tissue region. This method offers a prognostic tool for the study of the effects of experimental vasoactive therapy on liver microcirculation and perspectives for continuous monitoring of human liver microperfusion after liver surgery and trauma." @default.
• W2067951904 created "2016-06-24" @default.
• W2067951904 creator A5003961076 @default.
• W2067951904 creator A5005893112 @default.
• W2067951904 creator A5007652636 @default.
• W2067951904 creator A5016187305 @default.
• W2067951904 creator A5018658085 @default.
• W2067951904 creator A5023242832 @default.
• W2067951904 creator A5043009641 @default.
• W2067951904 creator A5045047262 @default.
• W2067951904 creator A5063413978 @default.
• W2067951904 creator A5079577958 @default.
• W2067951904 creator A5088990699 @default.
• W2067951904 creator A5090456267 @default.
• W2067951904 date "2004-01-01" @default.
• W2067951904 modified "2023-10-03" @default.
• W2067951904 title "Assessment of hepatic ischemia–reperfusion injury by simultaneous measurement of tissue pO2, pCO2, and pH" @default.
• W2067951904 cites W1409744500 @default.
• W2067951904 cites W1892024851 @default.
• W2067951904 cites W1964493106 @default.
• W2067951904 cites W1971328499 @default.
• W2067951904 cites W1986670762 @default.
• W2067951904 cites W1987180647 @default.
• W2067951904 cites W1988793653 @default.
• W2067951904 cites W1990199366 @default.
• W2067951904 cites W2004103677 @default.
• W2067951904 cites W2010844371 @default.
• W2067951904 cites W2012049756 @default.
• W2067951904 cites W2015795623 @default.
• W2067951904 cites W2022552037 @default.
• W2067951904 cites W2024884563 @default.
• W2067951904 cites W2027790935 @default.
• W2067951904 cites W2037284375 @default.
• W2067951904 cites W2040277963 @default.
• W2067951904 cites W2040308603 @default.
• W2067951904 cites W2046432740 @default.
• W2067951904 cites W2049958465 @default.
• W2067951904 cites W2054381541 @default.
• W2067951904 cites W2060117625 @default.
• W2067951904 cites W2072740336 @default.
• W2067951904 cites W2080285550 @default.
• W2067951904 cites W2081828836 @default.
• W2067951904 cites W2095135692 @default.
• W2067951904 cites W2095620436 @default.
• W2067951904 cites W2150914609 @default.
• W2067951904 cites W2152063232 @default.
• W2067951904 cites W2162804111 @default.
• W2067951904 cites W2404106741 @default.
• W2067951904 cites W2408673183 @default.
• W2067951904 doi "https://doi.org/10.1016/j.mvr.2003.09.002" @default.
• W2067951904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14709401" @default.
• W2067951904 hasPublicationYear "2004" @default.
• W2067951904 type Work @default.
• W2067951904 sameAs 2067951904 @default.
• W2067951904 citedByCount "19" @default.
• W2067951904 countsByYear W20679519042014 @default.
• W2067951904 countsByYear W20679519042016 @default.
• W2067951904 countsByYear W20679519042019 @default.
• W2067951904 crossrefType "journal-article" @default.
• W2067951904 hasAuthorship W2067951904A5003961076 @default.
• W2067951904 hasAuthorship W2067951904A5005893112 @default.
• W2067951904 hasAuthorship W2067951904A5007652636 @default.
• W2067951904 hasAuthorship W2067951904A5016187305 @default.
• W2067951904 hasAuthorship W2067951904A5018658085 @default.
• W2067951904 hasAuthorship W2067951904A5023242832 @default.
• W2067951904 hasAuthorship W2067951904A5043009641 @default.
• W2067951904 hasAuthorship W2067951904A5045047262 @default.
• W2067951904 hasAuthorship W2067951904A5063413978 @default.
• W2067951904 hasAuthorship W2067951904A5079577958 @default.
• W2067951904 hasAuthorship W2067951904A5088990699 @default.
• W2067951904 hasAuthorship W2067951904A5090456267 @default.
• W2067951904 hasConcept C126322002 @default.
• W2067951904 hasConcept C149601957 @default.
• W2067951904 hasConcept C158846371 @default.
• W2067951904 hasConcept C170493617 @default.
• W2067951904 hasConcept C178853913 @default.
• W2067951904 hasConcept C185592680 @default.
• W2067951904 hasConcept C2777140959 @default.
• W2067951904 hasConcept C2777397205 @default.
• W2067951904 hasConcept C2780114680 @default.
• W2067951904 hasConcept C2910183285 @default.
• W2067951904 hasConcept C42219234 @default.
• W2067951904 hasConcept C52305850 @default.
• W2067951904 hasConcept C541997718 @default.
• W2067951904 hasConcept C70289976 @default.
• W2067951904 hasConcept C71924100 @default.
• W2067951904 hasConceptScore W2067951904C126322002 @default.
• W2067951904 hasConceptScore W2067951904C149601957 @default.
• W2067951904 hasConceptScore W2067951904C158846371 @default.
• W2067951904 hasConceptScore W2067951904C170493617 @default.
• W2067951904 hasConceptScore W2067951904C178853913 @default.
• W2067951904 hasConceptScore W2067951904C185592680 @default.
• W2067951904 hasConceptScore W2067951904C2777140959 @default.
• W2067951904 hasConceptScore W2067951904C2777397205 @default.
• W2067951904 hasConceptScore W2067951904C2780114680 @default.
• W2067951904 hasConceptScore W2067951904C2910183285 @default.
• W2067951904 hasConceptScore W2067951904C42219234 @default.
• W2067951904 hasConceptScore W2067951904C52305850 @default.

• next