FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067979054> ?p ?o ?g. }

• W2067979054 endingPage "182" @default.
• W2067979054 startingPage "173" @default.
• W2067979054 abstract "Short term tissue biopsy cultures and paired, sera, bile and gastric and intestinal contents from Helicobacter pylori-infected gnotobiotic piglets were tested for the synthesis of H. pylori-specific immunoglobulin (Ig) isotype production by antigen-specific ELISA from post-infection days (PIDs) 2–28. Serum antibody levels in all three Ig isotypes were elevated from baseline values by PID 14, serum IgM levels reached peak levels on PID 14 and by PID 28 bile was strongly positive for IgA and IgG. Intestinal, but not gastric contents from infected piglets, contained IgA-specific antibody from PID 14 onward. Gastric mucosal epithelia adjacent to areas of inflammation in infected but not uninfected control piglets produced readily detectable amounts of porcine secretory component (SC); IgA-positive plasma cells were identified in gastric submucosa and lamina propria in these areas. Culture fluid supernatants, collected from explanted gastric cardia and antra and intestinal ilea of H. pylori-infected piglets had trace amounts of IgA as early as PID 2 in some animals, and strong IgA reactivity in all by PID 28. Supernatants also contained H. pylori-specific IgG by PID 14. A strong gastric lymph node IgA response contrasted with moderate IgA production in mesenteric lymph nodes and spleen. Mucosal biopsy production of H. pylori-specific IgG was more evenly distributed throughout the lymphoid system. These data support the contention that the Ig response to H. pylori is initiated within the gastric compartment and matures over time to a generalized IgA-dominated mucosal and IgG-dominated nonmucosal humoral immune response." @default.
• W2067979054 created "2016-06-24" @default.
• W2067979054 creator A5017737032 @default.
• W2067979054 creator A5066157304 @default.
• W2067979054 date "2002-09-01" @default.
• W2067979054 modified "2023-10-18" @default.
• W2067979054 title "Helicobacter pylori-specific immunoglobulin synthesis in gnotobiotic piglets: evidence for the induction of mucosal immunity in the stomach" @default.
• W2067979054 cites W1669654299 @default.
• W2067979054 cites W1895526710 @default.
• W2067979054 cites W1921696679 @default.
• W2067979054 cites W1947139787 @default.
• W2067979054 cites W1974393441 @default.
• W2067979054 cites W1984499682 @default.
• W2067979054 cites W1990692443 @default.
• W2067979054 cites W2003647849 @default.
• W2067979054 cites W2010459522 @default.
• W2067979054 cites W2050805196 @default.
• W2067979054 cites W2051705654 @default.
• W2067979054 cites W2060470998 @default.
• W2067979054 cites W2078137314 @default.
• W2067979054 cites W2107078862 @default.
• W2067979054 cites W2115122569 @default.
• W2067979054 cites W2117156032 @default.
• W2067979054 cites W2137832723 @default.
• W2067979054 cites W2149927437 @default.
• W2067979054 cites W2160416740 @default.
• W2067979054 cites W2163682172 @default.
• W2067979054 cites W2166833524 @default.
• W2067979054 cites W2170356588 @default.
• W2067979054 cites W2315067184 @default.
• W2067979054 cites W2321082521 @default.
• W2067979054 cites W2321415533 @default.
• W2067979054 cites W2330457764 @default.
• W2067979054 cites W2333840900 @default.
• W2067979054 cites W4298304256 @default.
• W2067979054 doi "https://doi.org/10.1016/s0165-2427(02)00164-2" @default.
• W2067979054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12127415" @default.
• W2067979054 hasPublicationYear "2002" @default.
• W2067979054 type Work @default.
• W2067979054 sameAs 2067979054 @default.
• W2067979054 citedByCount "9" @default.
• W2067979054 countsByYear W20679790542012 @default.
• W2067979054 countsByYear W20679790542013 @default.
• W2067979054 countsByYear W20679790542023 @default.
• W2067979054 crossrefType "journal-article" @default.
• W2067979054 hasAuthorship W2067979054A5017737032 @default.
• W2067979054 hasAuthorship W2067979054A5066157304 @default.
• W2067979054 hasConcept C147483822 @default.
• W2067979054 hasConcept C159654299 @default.
• W2067979054 hasConcept C181152851 @default.
• W2067979054 hasConcept C203014093 @default.
• W2067979054 hasConcept C2776409635 @default.
• W2067979054 hasConcept C2777068557 @default.
• W2067979054 hasConcept C2777310793 @default.
• W2067979054 hasConcept C2777991845 @default.
• W2067979054 hasConcept C2778677798 @default.
• W2067979054 hasConcept C2779102806 @default.
• W2067979054 hasConcept C2779422922 @default.
• W2067979054 hasConcept C2780898057 @default.
• W2067979054 hasConcept C529295009 @default.
• W2067979054 hasConcept C542903549 @default.
• W2067979054 hasConcept C54355233 @default.
• W2067979054 hasConcept C55493867 @default.
• W2067979054 hasConcept C86803240 @default.
• W2067979054 hasConcept C8891405 @default.
• W2067979054 hasConcept C89423630 @default.
• W2067979054 hasConceptScore W2067979054C147483822 @default.
• W2067979054 hasConceptScore W2067979054C159654299 @default.
• W2067979054 hasConceptScore W2067979054C181152851 @default.
• W2067979054 hasConceptScore W2067979054C203014093 @default.
• W2067979054 hasConceptScore W2067979054C2776409635 @default.
• W2067979054 hasConceptScore W2067979054C2777068557 @default.
• W2067979054 hasConceptScore W2067979054C2777310793 @default.
• W2067979054 hasConceptScore W2067979054C2777991845 @default.
• W2067979054 hasConceptScore W2067979054C2778677798 @default.
• W2067979054 hasConceptScore W2067979054C2779102806 @default.
• W2067979054 hasConceptScore W2067979054C2779422922 @default.
• W2067979054 hasConceptScore W2067979054C2780898057 @default.
• W2067979054 hasConceptScore W2067979054C529295009 @default.
• W2067979054 hasConceptScore W2067979054C542903549 @default.
• W2067979054 hasConceptScore W2067979054C54355233 @default.
• W2067979054 hasConceptScore W2067979054C55493867 @default.
• W2067979054 hasConceptScore W2067979054C86803240 @default.
• W2067979054 hasConceptScore W2067979054C8891405 @default.
• W2067979054 hasConceptScore W2067979054C89423630 @default.
• W2067979054 hasIssue "3-4" @default.
• W2067979054 hasLocation W20679790541 @default.
• W2067979054 hasLocation W20679790542 @default.
• W2067979054 hasOpenAccess W2067979054 @default.
• W2067979054 hasPrimaryLocation W20679790541 @default.
• W2067979054 hasRelatedWork W1606664295 @default.
• W2067979054 hasRelatedWork W1931067834 @default.
• W2067979054 hasRelatedWork W1935566751 @default.
• W2067979054 hasRelatedWork W1986556600 @default.
• W2067979054 hasRelatedWork W2081075548 @default.
• W2067979054 hasRelatedWork W2099244599 @default.
• W2067979054 hasRelatedWork W2102440256 @default.
• W2067979054 hasRelatedWork W2168146538 @default.

• next