Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067987642> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2067987642 abstract "Fujinami sarcoma virus (FSV) and PRCII are avian sarcoma viruses which share cellularly derived v-fps transforming sequences. The FSV P140gag-fps gene product is phosphorylated on three distinct tyrosine residues in transformed cells or in an in vitro kinase reaction. Three variants of FSV, and the related virus PRCII which lacks about half of the v-fps sequence found in FSV, encode gene products which are all phosphorylated at tyrosine residues contained within identical tryptic peptides. This indicates a stringent conservation of amino acid sequence at the tyrosine phosphorylation sites which presumably reflects the importance of these sites for the biologic activity of the transforming proteins. Under suitable conditions the proteolytic enzymes p15 and V8 protease each introduce one cut into FSV P140, p15 in the N-terminal gag-encoded region and V8 protease in the middle of the fps-encoded region. Using these enzymes we have mapped the major site of tyrosine phosphorylation to the C-terminal end of the fps region of FSV P140gag-fps. A second tyrosine phosphorylation site is found in the fps region of FSV P140 isolated from transformed cells, and a minor tyrosine phosphorylation site is found in the N-terminal gag-encoded region. Our results suggest that the C-terminal fps-encoded region is required for expression of the tyrosine-specific protein kinase activity." @default.
- W2067987642 created "2016-06-24" @default.
- W2067987642 creator A5077093856 @default.
- W2067987642 creator A5080777821 @default.
- W2067987642 date "1982-01-01" @default.
- W2067987642 modified "2023-09-27" @default.
- W2067987642 title "Localization and characterization of phosphorylation sites of the fujinami avian sarcoma virus and prcii virus transforming proteins" @default.
- W2067987642 cites W1487674467 @default.
- W2067987642 cites W1502987861 @default.
- W2067987642 cites W1503022671 @default.
- W2067987642 cites W1632169880 @default.
- W2067987642 cites W1728266132 @default.
- W2067987642 cites W1772190065 @default.
- W2067987642 cites W1811555672 @default.
- W2067987642 cites W1832627308 @default.
- W2067987642 cites W1954522192 @default.
- W2067987642 cites W1955985260 @default.
- W2067987642 cites W1970849188 @default.
- W2067987642 cites W1974768251 @default.
- W2067987642 cites W1975611863 @default.
- W2067987642 cites W1976353686 @default.
- W2067987642 cites W1980294596 @default.
- W2067987642 cites W1999100318 @default.
- W2067987642 cites W2005356524 @default.
- W2067987642 cites W2017560084 @default.
- W2067987642 cites W2027722451 @default.
- W2067987642 cites W2032309880 @default.
- W2067987642 cites W2034786653 @default.
- W2067987642 cites W2043631580 @default.
- W2067987642 cites W2054898895 @default.
- W2067987642 cites W2056770304 @default.
- W2067987642 cites W2081930669 @default.
- W2067987642 cites W2082522919 @default.
- W2067987642 cites W2111245799 @default.
- W2067987642 cites W2111941226 @default.
- W2067987642 cites W2164358316 @default.
- W2067987642 cites W2317587665 @default.
- W2067987642 cites W4240085856 @default.
- W2067987642 doi "https://doi.org/10.1002/jcb.240200404" @default.
- W2067987642 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6190824" @default.
- W2067987642 hasPublicationYear "1982" @default.
- W2067987642 type Work @default.
- W2067987642 sameAs 2067987642 @default.
- W2067987642 citedByCount "3" @default.
- W2067987642 countsByYear W20679876422017 @default.
- W2067987642 crossrefType "journal-article" @default.
- W2067987642 hasAuthorship W2067987642A5077093856 @default.
- W2067987642 hasAuthorship W2067987642A5080777821 @default.
- W2067987642 hasConcept C104317684 @default.
- W2067987642 hasConcept C11960822 @default.
- W2067987642 hasConcept C153911025 @default.
- W2067987642 hasConcept C2776165026 @default.
- W2067987642 hasConcept C2777553839 @default.
- W2067987642 hasConcept C42362537 @default.
- W2067987642 hasConcept C55493867 @default.
- W2067987642 hasConcept C62478195 @default.
- W2067987642 hasConcept C85528070 @default.
- W2067987642 hasConcept C86803240 @default.
- W2067987642 hasConceptScore W2067987642C104317684 @default.
- W2067987642 hasConceptScore W2067987642C11960822 @default.
- W2067987642 hasConceptScore W2067987642C153911025 @default.
- W2067987642 hasConceptScore W2067987642C2776165026 @default.
- W2067987642 hasConceptScore W2067987642C2777553839 @default.
- W2067987642 hasConceptScore W2067987642C42362537 @default.
- W2067987642 hasConceptScore W2067987642C55493867 @default.
- W2067987642 hasConceptScore W2067987642C62478195 @default.
- W2067987642 hasConceptScore W2067987642C85528070 @default.
- W2067987642 hasConceptScore W2067987642C86803240 @default.
- W2067987642 hasLocation W20679876421 @default.
- W2067987642 hasLocation W20679876422 @default.
- W2067987642 hasOpenAccess W2067987642 @default.
- W2067987642 hasPrimaryLocation W20679876421 @default.
- W2067987642 hasRelatedWork W1562710579 @default.
- W2067987642 hasRelatedWork W1580168755 @default.
- W2067987642 hasRelatedWork W1635131150 @default.
- W2067987642 hasRelatedWork W1969832217 @default.
- W2067987642 hasRelatedWork W2019151336 @default.
- W2067987642 hasRelatedWork W2055675186 @default.
- W2067987642 hasRelatedWork W2062816718 @default.
- W2067987642 hasRelatedWork W2183062661 @default.
- W2067987642 hasRelatedWork W2314622952 @default.
- W2067987642 hasRelatedWork W277666797 @default.
- W2067987642 isParatext "false" @default.
- W2067987642 isRetracted "false" @default.
- W2067987642 magId "2067987642" @default.
- W2067987642 workType "article" @default.