FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068011246> ?p ?o ?g. }

• W2068011246 endingPage "655" @default.
• W2068011246 startingPage "649" @default.
• W2068011246 abstract "The drug-drug interaction of two pMDI (pressure metered dose inhaler) combination products budesonide-formoterol fumarate dihydrate and salmeterol xinafoate-fluticasone propionate were investigated using in situ atomic force microscopy (AFM), equipped with a liquid cell filled with model a propellant, and Raman spectroscopy. Electron microscopy images of the budesonide-formoterol formulation suggested discrete particulates while the salmeterol-fluticasone formulation appeared agglomerated. Based on the analysis of the AFM curves, it is proposed that interactions in the budesonide-formoterol system (cohesion and adhesion) are dominated by van der Waals forces while interactions between salmeterol and fluticasone are of a chemical nature. Such observations are further substantiated by analysis of the Raman maps produced from pMDI actuations deposited on Andersen cascade impactor plates. The relevance of such synergy between particulates of different chemical nature is discussed. In particular, it is anticipated that strong interactions between particles could lead to heteroflocculation, increase aerosol particle size and consequently reduction of the respirable fine particle fraction." @default.
• W2068011246 created "2016-06-24" @default.
• W2068011246 creator A5012646235 @default.
• W2068011246 creator A5017452299 @default.
• W2068011246 creator A5025418280 @default.
• W2068011246 creator A5058017270 @default.
• W2068011246 creator A5087142025 @default.
• W2068011246 date "2011-09-01" @default.
• W2068011246 modified "2023-10-14" @default.
• W2068011246 title "Particle synergy and aerosol performance in non-aqueous liquid of two combinations metered dose inhalation formulations: An AFM and Raman investigation" @default.
• W2068011246 cites W123982374 @default.
• W2068011246 cites W1973547805 @default.
• W2068011246 cites W1981107716 @default.
• W2068011246 cites W1983805127 @default.
• W2068011246 cites W1993041699 @default.
• W2068011246 cites W2009692390 @default.
• W2068011246 cites W2017670360 @default.
• W2068011246 cites W2019762520 @default.
• W2068011246 cites W2022069744 @default.
• W2068011246 cites W2025591249 @default.
• W2068011246 cites W2028637591 @default.
• W2068011246 cites W2030537658 @default.
• W2068011246 cites W2056805649 @default.
• W2068011246 cites W2067242600 @default.
• W2068011246 cites W2075506397 @default.
• W2068011246 cites W2090801132 @default.
• W2068011246 cites W2094129304 @default.
• W2068011246 cites W2108690975 @default.
• W2068011246 cites W2112896993 @default.
• W2068011246 cites W2120629366 @default.
• W2068011246 cites W2127493805 @default.
• W2068011246 cites W2133688128 @default.
• W2068011246 cites W2140718395 @default.
• W2068011246 cites W2148518515 @default.
• W2068011246 cites W4236324887 @default.
• W2068011246 doi "https://doi.org/10.1016/j.jcis.2011.05.073" @default.
• W2068011246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21714970" @default.
• W2068011246 hasPublicationYear "2011" @default.
• W2068011246 type Work @default.
• W2068011246 sameAs 2068011246 @default.
• W2068011246 citedByCount "28" @default.
• W2068011246 countsByYear W20680112462012 @default.
• W2068011246 countsByYear W20680112462013 @default.
• W2068011246 countsByYear W20680112462014 @default.
• W2068011246 countsByYear W20680112462015 @default.
• W2068011246 countsByYear W20680112462016 @default.
• W2068011246 countsByYear W20680112462017 @default.
• W2068011246 countsByYear W20680112462018 @default.
• W2068011246 countsByYear W20680112462021 @default.
• W2068011246 crossrefType "journal-article" @default.
• W2068011246 hasAuthorship W2068011246A5012646235 @default.
• W2068011246 hasAuthorship W2068011246A5017452299 @default.
• W2068011246 hasAuthorship W2068011246A5025418280 @default.
• W2068011246 hasAuthorship W2068011246A5058017270 @default.
• W2068011246 hasAuthorship W2068011246A5087142025 @default.
• W2068011246 hasConcept C105702510 @default.
• W2068011246 hasConcept C111368507 @default.
• W2068011246 hasConcept C113196181 @default.
• W2068011246 hasConcept C120665830 @default.
• W2068011246 hasConcept C121332964 @default.
• W2068011246 hasConcept C127313418 @default.
• W2068011246 hasConcept C127413603 @default.
• W2068011246 hasConcept C147789679 @default.
• W2068011246 hasConcept C178790620 @default.
• W2068011246 hasConcept C185592680 @default.
• W2068011246 hasConcept C187530423 @default.
• W2068011246 hasConcept C2776136866 @default.
• W2068011246 hasConcept C2776719499 @default.
• W2068011246 hasConcept C2776954882 @default.
• W2068011246 hasConcept C2778517922 @default.
• W2068011246 hasConcept C2779028295 @default.
• W2068011246 hasConcept C2779345167 @default.
• W2068011246 hasConcept C2779871671 @default.
• W2068011246 hasConcept C2781212218 @default.
• W2068011246 hasConcept C2909086917 @default.
• W2068011246 hasConcept C40003534 @default.
• W2068011246 hasConcept C42360764 @default.
• W2068011246 hasConcept C43617362 @default.
• W2068011246 hasConcept C71924100 @default.
• W2068011246 hasConceptScore W2068011246C105702510 @default.
• W2068011246 hasConceptScore W2068011246C111368507 @default.
• W2068011246 hasConceptScore W2068011246C113196181 @default.
• W2068011246 hasConceptScore W2068011246C120665830 @default.
• W2068011246 hasConceptScore W2068011246C121332964 @default.
• W2068011246 hasConceptScore W2068011246C127313418 @default.
• W2068011246 hasConceptScore W2068011246C127413603 @default.
• W2068011246 hasConceptScore W2068011246C147789679 @default.
• W2068011246 hasConceptScore W2068011246C178790620 @default.
• W2068011246 hasConceptScore W2068011246C185592680 @default.
• W2068011246 hasConceptScore W2068011246C187530423 @default.
• W2068011246 hasConceptScore W2068011246C2776136866 @default.
• W2068011246 hasConceptScore W2068011246C2776719499 @default.
• W2068011246 hasConceptScore W2068011246C2776954882 @default.
• W2068011246 hasConceptScore W2068011246C2778517922 @default.
• W2068011246 hasConceptScore W2068011246C2779028295 @default.
• W2068011246 hasConceptScore W2068011246C2779345167 @default.
• W2068011246 hasConceptScore W2068011246C2779871671 @default.
• W2068011246 hasConceptScore W2068011246C2781212218 @default.

• next