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• W2068048633 abstract "Background: Malignant gastric outlet obstruction is the late complication of gastric, pancreatic, bile duct and GB cancer. Gastric stenosis (GS) is caused by advanced gastric cancer with direct tumor growth. In contrast, duodenal stenosis (DS) is caused by pancreatic, bile duct and GB cancer with extrinsic compression. Gastric outlet obstruction can be subdivided to GS and DS. In this study, we compare the feasibility, effectiveness, and outcome of covered and uncovered stent in GS and DS. Methods: 136 patients (88 men, 48 women: mean age 64.3) presenting gastric outlet obstruction with inoperable malignancy underwent endoscopic stent insertion. Results: All of the GS of 100 patients were caused by advanced gastric cancer and were treated with the insertion of covered (n = 41) and uncovered stent (n = 59). Covered and uncovered stents were inserted for 15 and 21 patients of 36 DS. Stent insertion and stent deployment were successful in all cases of GS and DS. Clinical success rates of covered and uncovered stent were 98% (55/56) and 97.5% (78/80). There was no procedure-related mortality. Overall stent complications were tumor ingrowth (covered 3.7%, uncovered 18.2%; p = 0.0084), overgrowth (3.7%, 0%; p = 0.08) and migration (16.3%, 0%; p = 0.0002). The rate of additional intervention was similar (23.3%, 18.2%; p = 0.56). Stent complication rate was divided on the location of stenosis. The complication pattern of GS was similar to overall complication-ingrowth (2.5%, 23%; p = 0.0045), overgrowth (5%, 0%; p = 0.09), migration (17.5%, 0%; p=0.0011), and the rate of additional intervention (25%, 23%; p = 0.83). But there was no significant difference in DS- ingrowth (6.6%, 9.5%; p = 0.75), overgrowth (0%, 0%), migration (13.3%, 0%; p = 0.085), the rate of additional intervention (20%, 9%; p = 0.37). Overall stent patency duration was similar (108 ± 12.6, 91 ± 9.9; p = 0.23). For GS, the patency duration of covered stent was significantly longer than that of uncovered stent (133 ± 16.8, 92.5 ± 10.8, p = 0.023). The patency duration of covered and uncovered stent was similar for DS (62 ± 13.1, 86.7 ± 23.1; p = 0.31). Conclusion: Endoscopic stent insertion is very effective treatment for maliganant gastric outlet obstruction and Covered stent is suitable for malignant gastric obstruction for long stent duration. Background: Malignant gastric outlet obstruction is the late complication of gastric, pancreatic, bile duct and GB cancer. Gastric stenosis (GS) is caused by advanced gastric cancer with direct tumor growth. In contrast, duodenal stenosis (DS) is caused by pancreatic, bile duct and GB cancer with extrinsic compression. Gastric outlet obstruction can be subdivided to GS and DS. In this study, we compare the feasibility, effectiveness, and outcome of covered and uncovered stent in GS and DS. Methods: 136 patients (88 men, 48 women: mean age 64.3) presenting gastric outlet obstruction with inoperable malignancy underwent endoscopic stent insertion. Results: All of the GS of 100 patients were caused by advanced gastric cancer and were treated with the insertion of covered (n = 41) and uncovered stent (n = 59). Covered and uncovered stents were inserted for 15 and 21 patients of 36 DS. Stent insertion and stent deployment were successful in all cases of GS and DS. Clinical success rates of covered and uncovered stent were 98% (55/56) and 97.5% (78/80). There was no procedure-related mortality. Overall stent complications were tumor ingrowth (covered 3.7%, uncovered 18.2%; p = 0.0084), overgrowth (3.7%, 0%; p = 0.08) and migration (16.3%, 0%; p = 0.0002). The rate of additional intervention was similar (23.3%, 18.2%; p = 0.56). Stent complication rate was divided on the location of stenosis. The complication pattern of GS was similar to overall complication-ingrowth (2.5%, 23%; p = 0.0045), overgrowth (5%, 0%; p = 0.09), migration (17.5%, 0%; p=0.0011), and the rate of additional intervention (25%, 23%; p = 0.83). But there was no significant difference in DS- ingrowth (6.6%, 9.5%; p = 0.75), overgrowth (0%, 0%), migration (13.3%, 0%; p = 0.085), the rate of additional intervention (20%, 9%; p = 0.37). Overall stent patency duration was similar (108 ± 12.6, 91 ± 9.9; p = 0.23). For GS, the patency duration of covered stent was significantly longer than that of uncovered stent (133 ± 16.8, 92.5 ± 10.8, p = 0.023). The patency duration of covered and uncovered stent was similar for DS (62 ± 13.1, 86.7 ± 23.1; p = 0.31). Conclusion: Endoscopic stent insertion is very effective treatment for maliganant gastric outlet obstruction and Covered stent is suitable for malignant gastric obstruction for long stent duration." @default.
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• W2068048633 title "Comparison of Covered and Uncovered Stent for Malignant Gastric and Duodenal Stenosis: Which Type of Stent Is Preferred According to the Site of Stenosis" @default.
• W2068048633 doi "https://doi.org/10.1016/s0016-5107(05)00967-3" @default.
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