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- W2068049270 endingPage "1148" @default.
- W2068049270 startingPage "1144" @default.
- W2068049270 abstract "Single-molecule force experiments in vitro enable the characterization of the mechanical response of biological matter at the nanometer scale. However, they do not reveal the molecular mechanisms underlying mechanical function. These can only be readily studied through molecular dynamics simulations of atomic structural models: “in silico” (by computer analysis) single-molecule experiments. Steered molecular dynamics simulations, in which external forces are used to explore the response and function of macromolecules, have become a powerful tool complementing and guiding in vitro single-molecule experiments. The insights provided by in silico experiments are illustrated here through a review of recent research in three areas of protein mechanics: elasticity of the muscle protein titin and the extracellular matrix protein fibronectin; linker-mediated elasticity of the cytoskeleton protein spectrin; and elasticity of ankyrin repeats, a protein module found ubiquitously in cells but with an as-yet unclear function." @default.
- W2068049270 created "2016-06-24" @default.
- W2068049270 creator A5029996336 @default.
- W2068049270 creator A5036622432 @default.
- W2068049270 date "2007-05-25" @default.
- W2068049270 modified "2023-10-18" @default.
- W2068049270 title "Single-Molecule Experiments in Vitro and in Silico" @default.
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- W2068049270 cites W1985900564 @default.
- W2068049270 cites W1988715261 @default.
- W2068049270 cites W1992280754 @default.
- W2068049270 cites W1996702954 @default.
- W2068049270 cites W1997828975 @default.
- W2068049270 cites W2000829418 @default.
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- W2068049270 doi "https://doi.org/10.1126/science.1137591" @default.
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