Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068049507> ?p ?o ?g. }
- W2068049507 endingPage "263" @default.
- W2068049507 startingPage "253" @default.
- W2068049507 abstract "Silver nanoparticles (AgNPs) have antibacterial characteristics, and currently are applied in Ag-containing products. This study found neural cells can uptake 3–5 nm AgNPs, and investigated the potential effects of AgNPs on gene expression of inflammation and neurodegenerative disorder in murine brain ALT astrocytes, microglial BV-2 cells and neuron N2a cells. After AgNPs (5, 10, 12.5 μg/ml) exposure, these neural cells had obviously increased IL-1β secretion, and induced gene expression of C-X-C motif chemokine 13 (CXCL13), macrophage receptor with collagenous structure (MARCO) and glutathione synthetase (GSS) for inflammatory response and oxidative stress neutralization. Additionally, this study found amyloid-β (Aβ) plaques for pathological feature of Alzheimer's disease (AD) deposited in neural cells after AgNPs treatment. After AgNPs exposure, the gene expression of amyloid precursor protein (APP) was induced, and otherwise, neprilysin (NEP) and low-density lipoprotein receptor (LDLR) were reduced in neural cells as well as protein level. These results suggested AgNPs could alter gene and protein expressions of Aβ deposition potentially to induce AD progress in neural cells. It's necessary to take notice of AgNPs distribution in the environment." @default.
- W2068049507 created "2016-06-24" @default.
- W2068049507 creator A5000883392 @default.
- W2068049507 creator A5018608548 @default.
- W2068049507 creator A5040985293 @default.
- W2068049507 creator A5061278139 @default.
- W2068049507 creator A5064786405 @default.
- W2068049507 creator A5091527248 @default.
- W2068049507 date "2015-01-01" @default.
- W2068049507 modified "2023-10-16" @default.
- W2068049507 title "Silver nanoparticles affect on gene expression of inflammatory and neurodegenerative responses in mouse brain neural cells" @default.
- W2068049507 cites W1744164530 @default.
- W2068049507 cites W1970411171 @default.
- W2068049507 cites W1972502322 @default.
- W2068049507 cites W1977348409 @default.
- W2068049507 cites W1986572176 @default.
- W2068049507 cites W1986623319 @default.
- W2068049507 cites W1992883702 @default.
- W2068049507 cites W2003816868 @default.
- W2068049507 cites W2006921654 @default.
- W2068049507 cites W2008154812 @default.
- W2068049507 cites W2010013310 @default.
- W2068049507 cites W2014897304 @default.
- W2068049507 cites W2016517325 @default.
- W2068049507 cites W2024746678 @default.
- W2068049507 cites W2026027491 @default.
- W2068049507 cites W2026723397 @default.
- W2068049507 cites W2030741867 @default.
- W2068049507 cites W2036735444 @default.
- W2068049507 cites W2036990194 @default.
- W2068049507 cites W2042694333 @default.
- W2068049507 cites W2050849699 @default.
- W2068049507 cites W2056202999 @default.
- W2068049507 cites W2057017636 @default.
- W2068049507 cites W2061643511 @default.
- W2068049507 cites W2069174062 @default.
- W2068049507 cites W2070441258 @default.
- W2068049507 cites W2073752435 @default.
- W2068049507 cites W2074661552 @default.
- W2068049507 cites W2077126954 @default.
- W2068049507 cites W2079891381 @default.
- W2068049507 cites W2089890681 @default.
- W2068049507 cites W2093005409 @default.
- W2068049507 cites W2098796119 @default.
- W2068049507 cites W2100557588 @default.
- W2068049507 cites W2112217999 @default.
- W2068049507 cites W2117353210 @default.
- W2068049507 cites W2125619729 @default.
- W2068049507 cites W2129972383 @default.
- W2068049507 cites W2133649359 @default.
- W2068049507 cites W2142467924 @default.
- W2068049507 cites W2144742773 @default.
- W2068049507 cites W2146795905 @default.
- W2068049507 cites W2156682269 @default.
- W2068049507 cites W2169612898 @default.
- W2068049507 cites W2321087602 @default.
- W2068049507 doi "https://doi.org/10.1016/j.envres.2014.11.006" @default.
- W2068049507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25460644" @default.
- W2068049507 hasPublicationYear "2015" @default.
- W2068049507 type Work @default.
- W2068049507 sameAs 2068049507 @default.
- W2068049507 citedByCount "124" @default.
- W2068049507 countsByYear W20680495072015 @default.
- W2068049507 countsByYear W20680495072016 @default.
- W2068049507 countsByYear W20680495072017 @default.
- W2068049507 countsByYear W20680495072018 @default.
- W2068049507 countsByYear W20680495072019 @default.
- W2068049507 countsByYear W20680495072020 @default.
- W2068049507 countsByYear W20680495072021 @default.
- W2068049507 countsByYear W20680495072022 @default.
- W2068049507 countsByYear W20680495072023 @default.
- W2068049507 crossrefType "journal-article" @default.
- W2068049507 hasAuthorship W2068049507A5000883392 @default.
- W2068049507 hasAuthorship W2068049507A5018608548 @default.
- W2068049507 hasAuthorship W2068049507A5040985293 @default.
- W2068049507 hasAuthorship W2068049507A5061278139 @default.
- W2068049507 hasAuthorship W2068049507A5064786405 @default.
- W2068049507 hasAuthorship W2068049507A5091527248 @default.
- W2068049507 hasBestOaLocation W20680495071 @default.
- W2068049507 hasConcept C104317684 @default.
- W2068049507 hasConcept C104826730 @default.
- W2068049507 hasConcept C116484652 @default.
- W2068049507 hasConcept C13373296 @default.
- W2068049507 hasConcept C150194340 @default.
- W2068049507 hasConcept C153911025 @default.
- W2068049507 hasConcept C154317977 @default.
- W2068049507 hasConcept C170493617 @default.
- W2068049507 hasConcept C181199279 @default.
- W2068049507 hasConcept C185592680 @default.
- W2068049507 hasConcept C202751555 @default.
- W2068049507 hasConcept C203014093 @default.
- W2068049507 hasConcept C2776914184 @default.
- W2068049507 hasConcept C538909803 @default.
- W2068049507 hasConcept C55493867 @default.
- W2068049507 hasConcept C79484868 @default.
- W2068049507 hasConcept C86803240 @default.
- W2068049507 hasConcept C87753298 @default.
- W2068049507 hasConcept C95444343 @default.