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- W2068055759 abstract "A series of dansylated fluorescent analogs was synthesized and tested for cholinergic and anticholinergic activity in Schistosoma mansoni. The compounds were compared with a previously reported analog, 5-(dimethylamino)-N-(2-dimethylaminoethyl)naphtha-lenesulfonamide hydrochloride (I). All of the compounds produced some fluorescent labeling of a structure in the head region of the worms. Major differences were not seen among the compounds. The compounds also were tested as antagonists of carbachol-induced paralysis in an activity monitor. Significant carbachol antagonism was seen for all compounds. Effects on the serotonin response also were recorded. Only one compound, a dibutylaminopropylamine derivative, produced striking antagonism of serotonin-induced motor activity." @default.
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- W2068055759 date "1980-05-01" @default.
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- W2068055759 title "Effects of dansylated acetylcholine analogs on Schistosoma mansoni" @default.
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- W2068055759 doi "https://doi.org/10.1002/jps.2600690510" @default.
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