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- W2068085493 abstract "During a 42-month period, we used plasmapheresis to treat four cases of myasthenia gravis with refractory respiratory failure. All four patients were ventilator dependent for prolonged periods and were not responding to management with cholinesterase inhibitors and corticosteroids. All four patients rapidly responded to the plasmapheresis; respiratory muscle strength returned sufficiently to allow discontinuation of assisted mechanical ventilation and removal of the artificial airway. In our experience, plasmapheresis is indicated in the treatment of the myasthenia gravis patient with respiratory failure which is refractory to conventional drug therapy. During a 42-month period, we used plasmapheresis to treat four cases of myasthenia gravis with refractory respiratory failure. All four patients were ventilator dependent for prolonged periods and were not responding to management with cholinesterase inhibitors and corticosteroids. All four patients rapidly responded to the plasmapheresis; respiratory muscle strength returned sufficiently to allow discontinuation of assisted mechanical ventilation and removal of the artificial airway. In our experience, plasmapheresis is indicated in the treatment of the myasthenia gravis patient with respiratory failure which is refractory to conventional drug therapy. Respiratory Failure in Myasthenia Gravis: Use of PlasmapheresisCHESTVol. 85Issue 6PreviewThe clinical manifestations of myasthenia gravis vary widely; the most seriously ill patients have bulbar and respiratory failure. The management of their condition may be extraordinarily difficult and requires outstanding collaborative interaction between nurses, respiratory therapists, and specialists in neurology, pulmonary medicine, and infectious disease. Even then, the outcome may be unsatisfactory because of failure to control the underlying disease process with conventional therapy consisting of anticholinesterase medications, thymectomy, and prednisone. Full-Text PDF" @default.
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- W2068085493 date "1984-06-01" @default.
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- W2068085493 title "Plasmapheresis in the Treatment of Ventilator-Dependent Myasthenia Gravis Patients" @default.
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- W2068085493 doi "https://doi.org/10.1378/chest.85.6.739" @default.
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