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• W2068117537 abstract "No AccessJournal of UrologyClinical Urology: Original Article1 Jul 1997Protease Inhibitors and Urolithiasis Suzette E. Sutherland, Melissa D. Reigle, Allen D. Seftel, and Martin I. Resnick Suzette E. SutherlandSuzette E. Sutherland More articles by this author , Melissa D. ReigleMelissa D. Reigle More articles by this author , Allen D. SeftelAllen D. Seftel More articles by this author , and Martin I. ResnickMartin I. Resnick More articles by this author View All Author Informationhttps://doi.org/10.1097/00005392-199707000-00007AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We discuss the specific urological abnormalities associated with protease inhibitor therapy. Materials and Methods: We report on a human immunodeficiency virus positive patient who was on protease inhibitor therapy and presented with renal colic. Results: The stone passed spontaneously. Stone analysis was not consistent with any known composition of urinary calculus. Conclusions: The positive effects of protease inhibitors in human immunodeficiency virus positive patients mandate that the urological community become familiar with these drugs and the specific urological complications as the use of these drugs becomes widespread. References 1 Deutsch, P., Teppler, H. and Squires, K.: Antiviral activity of L735-524, an HIV protease inhibitor, in infected patients. Read at Interscience Conference on Antimicrobial Agents and Chemotherapy, Florida, p. 159, 1994. Google Scholar 2 Stein, D. S., Fish, D. G. and Chodakewitz, J.: A 24 week open label phase I evaluation of the HIV protease inhibitor L735-524. Read at National Conference on Human Retroviruses and Related Infections, Washington, D.C., 1995. Google Scholar 3 Mellors, J., Steigbigel, R. and Gulick, R.: A randomized, double blind study of the oral HIV protease inhibitor L735-524 vs. zidovudine (ZDV) in p24 antigenemic, HIV-1 infected patients with 500 CD4 cells/mm3. Read at National Conference on Human Retroviruses and Related Infections, Washington, D.C., p. 183, 1995. Google Scholar 4 : HIV protease inhibitors. AIDS1995; 9: S183. Google Scholar 5 Chodakewitz, J., Deutsch, P. and Leavitt, R.: Preliminary evaluation of the long term safety & antiviral activity exerted by CRIXIVAN (MK-639), an oral HIV protease inhibitor. Read at European Conference on Clinical Aspects and Treatment of HIV Infection, Copenhagen, p. 7, 1995 Google Scholar 6 Gulick, T., Mellors, J. and Havlur, D.: Potent and sustained antiretroviral activity of indinavir (IDV) in combination with zidovudine (ADV) and lamivudine (3TC). Read at Conference on Retroviruses and Opportunistic Infections, Washington, D.C., p. 162, 1996. 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Read at Interscience Conference on Antimicrobial Agents and Chemotherapy, California, 1995 Google Scholar 25 : Provisional Public Health service recommendations for chemoprophylaxis after occupational-exposure to HIV. Morbid. Mortal. Weekly Rep.1996; 45: 468. Google Scholar From the Department of Urology, Case Western Reserve University, Cleveland Veterans Affairs Medical Center, University Hospitals of Cleveland, Cleveland, Ohio.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByNADLER R, RUBENSTEIN J, EGGENER S, LOOR M and SMITH N (2018) The Etiology of Urolithiasis in HIV Infected PatientsJournal of Urology, VOL. 169, NO. 2, (475-477), Online publication date: 1-Feb-2003.SALTEL E, ANGEL J, FUTTER N, WALSH W, O’ROURKE K and MAHONEY J (2018) INCREASED PREVALENCE AND ANALYSIS OF RISK FACTORS FOR INDINAVIR NEPHROLITHIASISJournal of Urology, VOL. 164, NO. 6, (1895-1897), Online publication date: 1-Dec-2000.REITER W, SCHON-PERNERSTORFER H, DORFINGER K, HOFBAUER J and MARBERGER M (2018) FREQUENCY OF UROLITHIASIS IN INDIVIDUALS SEROPOSITIVE FOR HUMAN IMMUNODEFICIENCY VIRUS TREATED WITH INDINAVIR IS HIGHER THAN PREVIOUSLY ASSUMEDJournal of Urology, VOL. 161, NO. 4, (1082-1084), Online publication date: 1-Apr-1999.KOHAN A, ARMENAKAS N and FRACCHIA J (2018) INDINAVIR UROLITHIASIS: AN EMERGING CAUSE OF RENAL COLIC IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUSJournal of Urology, VOL. 161, NO. 6, (1765-1768), Online publication date: 1-Jun-1999. (2018) EDITORIAL COMMENTJournal of Urology, VOL. 159, NO. 6, (2074-2075), Online publication date: 1-Jun-1998. Volume 158Issue 1July 1997Page: 31-33 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Suzette E. Sutherland More articles by this author Melissa D. Reigle More articles by this author Allen D. Seftel More articles by this author Martin I. Resnick More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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