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- W2068118624 abstract "(1SR,4RS)-3,3-Dimethyl-1,2,3,4-tetrahydro-1,4-(epiminomethano)naphthalenes were synthesized in 2–3 steps from commercially available materials and assessed for specificity and effectiveness across a range of Nox isoforms. The N-pentyl and N-methylenethiophene substituted analogs 11g and 11h emerged as selective Nox2 inhibitors with cellular IC50 values of 20 and 32 μM, respectively." @default.
- W2068118624 created "2016-06-24" @default.
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- W2068118624 date "2013-01-01" @default.
- W2068118624 modified "2023-09-30" @default.
- W2068118624 title "Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors" @default.
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- W2068118624 doi "https://doi.org/10.1039/c3md00061c" @default.
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