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- W2068132186 abstract "Proteomic analyses of zebra finch (Taeniopygia guttata) optic tectum resulted in identification of 176 proteins. In the Swissprot database, only 52 proteins were identified as bird homologs and only 71 proteins were identified in songbird transcriptome databases, reflecting a lack of completeness in the T. guttata genomic sequence. Analysis in Kyoto encyclopedia of genes and genome (KEGG) pathway database found that identified proteins most frequently belong to glucose, pyruvate, glyoxylate, dicarboxylate, alanine, and aspartate metabolism pathways. A number of identified proteins have been previously reported to exist in the avian optic tectum. The immunohistochemical localization of selected proteins showed their distribution in similar laminae of the owl (Tyto alba) and chicken (Gallus gallus) tectum. Immunohistochemical analysis of identified proteins can provide clues about cell types and circuit layout of the avian optic tectum in general. As the optic tectum of nonmammals is homologous to the superior colliculus of mammals, the analysis of the tectal and collicular proteome may provide clues about conserved cell and circuit layout, circuit function, and evolution. Keywords: zebra finch · optic tectum · proteome · circuit function · Taeniopygia guttata" @default.
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- W2068132186 date "2007-05-12" @default.
- W2068132186 modified "2023-09-25" @default.
- W2068132186 title "Proteomic Analyses of Zebra Finch Optic Tectum and Comparative Histochemistry" @default.
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- W2068132186 doi "https://doi.org/10.1021/pr070126w" @default.
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