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• W2068156698 abstract "We investigated the effects of an Na(+)/H(+) exchanger inhibitor, sabiporide, on excitotoxicity in cultured neuronal cells and in vivo. Sabiporide attenuated glutamate- or NMDA (N-methyl-d-aspartic acid)-induced neuronal cell death. Sabiporide also reduced glutamate or NMDA-induced increase in [Ca(2+)](i). In in vivo brain ischemia model, sabiporide produced protective effects, decreasing the infarct size and edema volume. Our results suggest that sabiporide elicits neuroprotective effect both in vitro and in vivo." @default.
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• W2068156698 date "2005-11-01" @default.
• W2068156698 modified "2023-09-25" @default.
• W2068156698 title "Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia" @default.
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• W2068156698 doi "https://doi.org/10.1016/j.brainres.2005.09.002" @default.
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