Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068157241> ?p ?o ?g. }
- W2068157241 endingPage "749" @default.
- W2068157241 startingPage "744" @default.
- W2068157241 abstract "Tumours of patients with node-positive rectal cancer were studied by immunohistochemistry for p53, BAX and vascular endothelial growth factor expressions. Results were correlated to the relapse rate, the pattern of relapse and the event-free survival after radical surgery and adjuvant chemoradiation. After a median follow-up of 60 months, 39 patients remained disease-free and 40 patients relapsed (18 local relapses and 22 distant metastases). The majority of disease-free patients showed p53 negative and vascular endothelial growth factor negative tumours. Local relapses occurred more frequently in patients with p53 overexpressing tumours (P<0.01), while distant metastases were in patients with vascular endothelial growth factor positive tumours (P<0.003). Patients with p53 negative or vascular endothelial growth factor negative tumours showed better event-free survival than patients with p53 positive or vascular endothelial growth factor positive tumours. BAX analysis did not show any association with patients' outcome and it was unrelated to the p53 status. Adjuvant treatment strategies for node-positive rectal cancer may be improved by identifying categories of high-risk patients. In this study, vascular endothelial growth factor and p53 expressions correlated with recurrent disease, pattern of relapse and poor event-free survival." @default.
- W2068157241 created "2016-06-24" @default.
- W2068157241 creator A5011248636 @default.
- W2068157241 creator A5018141422 @default.
- W2068157241 creator A5025410112 @default.
- W2068157241 creator A5038347927 @default.
- W2068157241 creator A5042028913 @default.
- W2068157241 creator A5042517744 @default.
- W2068157241 creator A5046163698 @default.
- W2068157241 creator A5061179981 @default.
- W2068157241 creator A5063303757 @default.
- W2068157241 creator A5067058355 @default.
- W2068157241 creator A5080715168 @default.
- W2068157241 date "2002-02-26" @default.
- W2068157241 modified "2023-10-06" @default.
- W2068157241 title "An analysis of p53, BAX and vascular endothelial growth factor expression in node-positive rectal cancer. Relationships with tumour recurrence and event-free survival of patients treated with adjuvant chemoradiation" @default.
- W2068157241 cites W1580556434 @default.
- W2068157241 cites W1586129343 @default.
- W2068157241 cites W1870720170 @default.
- W2068157241 cites W1892445025 @default.
- W2068157241 cites W1923484756 @default.
- W2068157241 cites W1967007810 @default.
- W2068157241 cites W1969026343 @default.
- W2068157241 cites W1975618936 @default.
- W2068157241 cites W1979041142 @default.
- W2068157241 cites W1981153827 @default.
- W2068157241 cites W1981938979 @default.
- W2068157241 cites W1983386156 @default.
- W2068157241 cites W2002230661 @default.
- W2068157241 cites W2005756701 @default.
- W2068157241 cites W2006184092 @default.
- W2068157241 cites W2014958910 @default.
- W2068157241 cites W2015159074 @default.
- W2068157241 cites W2015994232 @default.
- W2068157241 cites W2016780875 @default.
- W2068157241 cites W2018284015 @default.
- W2068157241 cites W2019270896 @default.
- W2068157241 cites W2031825047 @default.
- W2068157241 cites W2042316019 @default.
- W2068157241 cites W2045086385 @default.
- W2068157241 cites W2046177798 @default.
- W2068157241 cites W2046955889 @default.
- W2068157241 cites W2049852228 @default.
- W2068157241 cites W2074336818 @default.
- W2068157241 cites W2088098884 @default.
- W2068157241 cites W2088377055 @default.
- W2068157241 cites W2088395263 @default.
- W2068157241 cites W2095589295 @default.
- W2068157241 cites W2101914663 @default.
- W2068157241 cites W2104114689 @default.
- W2068157241 cites W2148296009 @default.
- W2068157241 cites W2253032222 @default.
- W2068157241 cites W2312261662 @default.
- W2068157241 cites W2319752208 @default.
- W2068157241 cites W2397241885 @default.
- W2068157241 cites W2415794729 @default.
- W2068157241 cites W2418044589 @default.
- W2068157241 cites W2418883000 @default.
- W2068157241 cites W2165916113 @default.
- W2068157241 doi "https://doi.org/10.1038/sj.bjc.6600155" @default.
- W2068157241 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2375295" @default.
- W2068157241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11875737" @default.
- W2068157241 hasPublicationYear "2002" @default.
- W2068157241 type Work @default.
- W2068157241 sameAs 2068157241 @default.
- W2068157241 citedByCount "42" @default.
- W2068157241 countsByYear W20681572412012 @default.
- W2068157241 countsByYear W20681572412013 @default.
- W2068157241 countsByYear W20681572412014 @default.
- W2068157241 countsByYear W20681572412015 @default.
- W2068157241 countsByYear W20681572412016 @default.
- W2068157241 countsByYear W20681572412022 @default.
- W2068157241 crossrefType "journal-article" @default.
- W2068157241 hasAuthorship W2068157241A5011248636 @default.
- W2068157241 hasAuthorship W2068157241A5018141422 @default.
- W2068157241 hasAuthorship W2068157241A5025410112 @default.
- W2068157241 hasAuthorship W2068157241A5038347927 @default.
- W2068157241 hasAuthorship W2068157241A5042028913 @default.
- W2068157241 hasAuthorship W2068157241A5042517744 @default.
- W2068157241 hasAuthorship W2068157241A5046163698 @default.
- W2068157241 hasAuthorship W2068157241A5061179981 @default.
- W2068157241 hasAuthorship W2068157241A5063303757 @default.
- W2068157241 hasAuthorship W2068157241A5067058355 @default.
- W2068157241 hasAuthorship W2068157241A5080715168 @default.
- W2068157241 hasBestOaLocation W20681572411 @default.
- W2068157241 hasConcept C121608353 @default.
- W2068157241 hasConcept C126322002 @default.
- W2068157241 hasConcept C142724271 @default.
- W2068157241 hasConcept C143998085 @default.
- W2068157241 hasConcept C167734588 @default.
- W2068157241 hasConcept C204232928 @default.
- W2068157241 hasConcept C2777025900 @default.
- W2068157241 hasConcept C2777982462 @default.
- W2068157241 hasConcept C526805850 @default.
- W2068157241 hasConcept C71924100 @default.
- W2068157241 hasConceptScore W2068157241C121608353 @default.
- W2068157241 hasConceptScore W2068157241C126322002 @default.
- W2068157241 hasConceptScore W2068157241C142724271 @default.