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• W2068177629 abstract "Research in the field of biological effects of heavy charged particles is needed for both heavy-ion therapy (hadrontherapy) and protection from the exposure to galactic cosmic radiation in long-term manned space missions. Although the exposure conditions (e.g. high- vs. low-dose rate) and relevant endpoints (e.g. cell killing vs. neoplastic transformation) are different in the two fields, it is clear that a substantial overlap exists in several research topics. Three such topics are discussed in this short review: individual radiosensitivity, mixed radiation fields, and late stochastic effects of heavy ions. In addition, researchers involved either in experimental studies on space radiation protection or heavy-ion therapy will basically use the same accelerator facilities. It seems to be important that novel accelerator facilities planned (or under construction) for heavy-ion therapy reserve a substantial amount of beamtime to basic studies of heavy-ion radiobiology and its applications in space radiation research. Research in the field of biological effects of heavy charged particles is needed for both heavy-ion therapy (hadrontherapy) and protection from the exposure to galactic cosmic radiation in long-term manned space missions. Although the exposure conditions (e.g. high- vs. low-dose rate) and relevant endpoints (e.g. cell killing vs. neoplastic transformation) are different in the two fields, it is clear that a substantial overlap exists in several research topics. Three such topics are discussed in this short review: individual radiosensitivity, mixed radiation fields, and late stochastic effects of heavy ions. In addition, researchers involved either in experimental studies on space radiation protection or heavy-ion therapy will basically use the same accelerator facilities. It seems to be important that novel accelerator facilities planned (or under construction) for heavy-ion therapy reserve a substantial amount of beamtime to basic studies of heavy-ion radiobiology and its applications in space radiation research." @default.
• W2068177629 created "2016-06-24" @default.
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• W2068177629 date "2004-12-01" @default.
• W2068177629 modified "2023-09-25" @default.
• W2068177629 title "Heavy ion radiobiology for hadrontherapy and space radiation protection" @default.
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• W2068177629 doi "https://doi.org/10.1016/s0167-8140(04)80040-9" @default.
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