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- W2068183729 abstract "By analyzing crosses between yeast strains carrying different combinations of mitochondrial (mt) introns, we have shown that the aI5α intron is mobile in vivo. Furthermore, we have observed that the mobility of intron aI5α is affected by both the nuclear and mt genotypes. We have also detected a restriction endonuclease (ENase) activity that cleaves intronless mt genomes close to the aI5α intron insertion site and thus might be involved in intron mobility. This is further supported by the fact that this ENase activity is only detected in a strain containing the aI5α intron. Furthermore, similar to other ENases encoded by mobile mt introns of yeast, the ENase generates a cut with a four-base 3′-OH overhang. Thus, intron aI5α represents a characteristic member of the family of mobile group-I introns." @default.
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- W2068183729 date "1992-04-01" @default.
- W2068183729 modified "2023-10-14" @default.
- W2068183729 title "The yeast mitochondrial intron aI5α: associated endonuclease activity and in vivo mobility" @default.
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- W2068183729 doi "https://doi.org/10.1016/0378-1119(92)90663-a" @default.
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