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- W2068190318 abstract "Recent studies have reported that remote organs are affected by renal ischemia reperfusion (IR). The present study investigates the role of vitamin E on the liver damage after renal IR. First, male mice were subjected to three groups (n = 9): 1) sham-operated, (2) renal IR (45 min ischemia), (3) renal IR + Vitamin E (150 mg/kg trough feeding tube for 28 d). After 24 h of reperfusion, animal were anesthetized for sample collections. Liver tissues malondialdehyde (MDA) increased and total glutathione (GSH) concentration decreased in the IR group compared to the sham group. Vitamin E consumption diminished the IR-induced increase in plasma AST and ALT. In addition, Vitamin E inhibited the IR-induced decrease in GSH activity and diminished IR-induced increase in MDA concentration. These findings showed that vitamin E consumption partly inhibited the IR-induced liver damage." @default.
- W2068190318 created "2016-06-24" @default.
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- W2068190318 date "2015-02-02" @default.
- W2068190318 modified "2023-09-23" @default.
- W2068190318 title "Protective effects of vitamin E against liver damage caused by renal ischemia reperfusion" @default.
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- W2068190318 doi "https://doi.org/10.3109/0886022x.2015.1006084" @default.
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