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• W2068202200 abstract "8–37 hCGRP is a potent antagonist at calcitonin gene‐related peptide (CGRP) liver membrane receptors; it also blocks vasodilator actions of CGRP and the related peptide, amylin, in intact rats. We now report that 8–37 hCGRP antagonizes amylin inhibition of insulin‐stimulated labelled glucose uptake into isolated rat soleus muscle, and inhibits amylin‐evoked elevation of plasma lactate and glucose in fasted anaesthetized rats. The different relative potencies of the 3 ligands (amylin, CGRP, 8–37 hCGRP) on the liver receptor and on the soleus muscle point to distinct CGRP receptors in liver membranes and amylin receptors on muscle cells." @default.
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• W2068202200 date "1991-10-21" @default.
• W2068202200 modified "2023-10-15" @default.
• W2068202200 title "^8-37 h-CGRP antagonizes actions of amylin on carbohydrate metabolism in vitro and in vivo" @default.
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• W2068202200 doi "https://doi.org/10.1016/0014-5793(91)81282-d" @default.
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