Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068222607> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2068222607 endingPage "2370" @default.
- W2068222607 startingPage "2363" @default.
- W2068222607 abstract "Hyperthermia enhances the cytocidal effect of ionizing radiation. Several pilot studies demonstrated that the combination of interstitial hyperthermia and interstitial radiotherapy (interstitial thermoradiotherapy) is safe and effective. However, these studies mainly utilized low dose rate brachytherapy, and therefore, required hospitalization. With the availability of median or high dose rate brachytherapy devices, we piloted a study to evaluate the feasibility, toxicity and efficacy of interstitial thermoradiotherapy performed in an outpatient setting.Between 1989 and 1993, 27 patients with a diagnosis of carcinoma of the head and neck region (n = 23), carcinoma of the breast (n = 3), or malignant melanoma (n = 1) received 1 or 2 sessions of interstitial thermoradiotherapy. Median patient age was 66 years (range: 37-83 years). Treatment consisted of 60 minutes of 915 MHz microwave interstitial hyperthermia, followed by iridium-192 seed implants, either by Micro-Selectron HDR (10-12 Gray [Gy] in 8.5-21 minutes) or high activity (5-8 mCi per seed) seeds (10-15 Gy in 2-4 hours). In addition to interstitial temperature measurements, a real-time thermal camera was used to monitor the surface temperature spatial distribution. power supply and/or position of interstitial microwave applicators was adjusted when appropriate. All but one patient also received external beam irradiation prior to implants.Patients tolerated treatments well although 16 (59%) of them required analgesics during hyperthermia sessions. Skin blisters or ulcerations occurred in only 6 (22%), and all but 2 healed. Complete response occurred in 24 patients (89%), partial in 3 (11%). With a median follow up of 16 months (range: 3-43 months), the 2-year actuarial local control rate was 74%.The results of this study indicate that outpatient interstitial thermoradiotherapy is convenient, safe, and efficacious for treating human neoplasms." @default.
- W2068222607 created "2016-06-24" @default.
- W2068222607 creator A5054648298 @default.
- W2068222607 creator A5063855164 @default.
- W2068222607 creator A5087728679 @default.
- W2068222607 date "1996-06-01" @default.
- W2068222607 modified "2023-10-18" @default.
- W2068222607 title "Outpatient interstitial thermoradiotherapy" @default.
- W2068222607 cites W1988268426 @default.
- W2068222607 cites W1994520573 @default.
- W2068222607 cites W2000144812 @default.
- W2068222607 cites W2002910462 @default.
- W2068222607 cites W2012096945 @default.
- W2068222607 cites W2029009395 @default.
- W2068222607 cites W2032071457 @default.
- W2068222607 cites W2032879249 @default.
- W2068222607 cites W2035745510 @default.
- W2068222607 cites W2037339820 @default.
- W2068222607 cites W2042998756 @default.
- W2068222607 cites W2043402257 @default.
- W2068222607 cites W2063307953 @default.
- W2068222607 cites W2081506397 @default.
- W2068222607 cites W2084895895 @default.
- W2068222607 cites W2086061695 @default.
- W2068222607 cites W2132167680 @default.
- W2068222607 cites W2160303481 @default.
- W2068222607 cites W2169773527 @default.
- W2068222607 cites W2462521067 @default.
- W2068222607 cites W4298328548 @default.
- W2068222607 doi "https://doi.org/10.1002/(sici)1097-0142(19960601)77:11<2363::aid-cncr27>3.0.co;2-u" @default.
- W2068222607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8635108" @default.
- W2068222607 hasPublicationYear "1996" @default.
- W2068222607 type Work @default.
- W2068222607 sameAs 2068222607 @default.
- W2068222607 citedByCount "2" @default.
- W2068222607 crossrefType "journal-article" @default.
- W2068222607 hasAuthorship W2068222607A5054648298 @default.
- W2068222607 hasAuthorship W2068222607A5063855164 @default.
- W2068222607 hasAuthorship W2068222607A5087728679 @default.
- W2068222607 hasConcept C126322002 @default.
- W2068222607 hasConcept C126838900 @default.
- W2068222607 hasConcept C141071460 @default.
- W2068222607 hasConcept C2777416452 @default.
- W2068222607 hasConcept C2779949491 @default.
- W2068222607 hasConcept C2989005 @default.
- W2068222607 hasConcept C509974204 @default.
- W2068222607 hasConcept C71924100 @default.
- W2068222607 hasConceptScore W2068222607C126322002 @default.
- W2068222607 hasConceptScore W2068222607C126838900 @default.
- W2068222607 hasConceptScore W2068222607C141071460 @default.
- W2068222607 hasConceptScore W2068222607C2777416452 @default.
- W2068222607 hasConceptScore W2068222607C2779949491 @default.
- W2068222607 hasConceptScore W2068222607C2989005 @default.
- W2068222607 hasConceptScore W2068222607C509974204 @default.
- W2068222607 hasConceptScore W2068222607C71924100 @default.
- W2068222607 hasIssue "11" @default.
- W2068222607 hasLocation W20682226071 @default.
- W2068222607 hasLocation W20682226072 @default.
- W2068222607 hasOpenAccess W2068222607 @default.
- W2068222607 hasPrimaryLocation W20682226071 @default.
- W2068222607 hasRelatedWork W1586374228 @default.
- W2068222607 hasRelatedWork W2003938723 @default.
- W2068222607 hasRelatedWork W2047967234 @default.
- W2068222607 hasRelatedWork W2118496982 @default.
- W2068222607 hasRelatedWork W2364998975 @default.
- W2068222607 hasRelatedWork W2369162477 @default.
- W2068222607 hasRelatedWork W2439875401 @default.
- W2068222607 hasRelatedWork W4220908969 @default.
- W2068222607 hasRelatedWork W4238867864 @default.
- W2068222607 hasRelatedWork W2525756941 @default.
- W2068222607 hasVolume "77" @default.
- W2068222607 isParatext "false" @default.
- W2068222607 isRetracted "false" @default.
- W2068222607 magId "2068222607" @default.
- W2068222607 workType "article" @default.