Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068258520> ?p ?o ?g. }
- W2068258520 endingPage "195" @default.
- W2068258520 startingPage "184" @default.
- W2068258520 abstract "Cell adhesion molecules of the Immunoglobulin Superfamily (IgCAMs) are key factors in nervous system formation. The contactin subgroup of IgCAMs consists of GPI-anchored glycoproteins implicated in axon outgrowth, guidance, fasciculation and neuronal differentiation. The mechanism by which contactins facilitate neuronal development is not understood. To gain insight into the function of contactins, we characterized RIG-6, the sole contactin of Caenorhabditis elegans. We show that the contactin RIG-6 is involved in excretory cell (EC) tubular elongation. We also show that RIG-6 mediates axon outgrowth and guidance along both the anterior-posterior and dorso-ventral axis, during C. elegans development. We find that optimal RIG-6 expression is critical for accurate mechanosensory neuron axon elongation and ventral nerve cord architecture. In addition, our data suggest that the cytoplasmic UNC-53/NAV2 proteins may contribute to relay signaling via contactins." @default.
- W2068258520 created "2016-06-24" @default.
- W2068258520 creator A5069467635 @default.
- W2068258520 creator A5071420074 @default.
- W2068258520 creator A5090655656 @default.
- W2068258520 date "2013-01-01" @default.
- W2068258520 modified "2023-10-16" @default.
- W2068258520 title "The contactin RIG-6 mediates neuronal and non-neuronal cell migration in Caenorhabditis elegans" @default.
- W2068258520 cites W1486450190 @default.
- W2068258520 cites W1545756296 @default.
- W2068258520 cites W1667125033 @default.
- W2068258520 cites W1904905451 @default.
- W2068258520 cites W1942193811 @default.
- W2068258520 cites W1944127002 @default.
- W2068258520 cites W1948927501 @default.
- W2068258520 cites W1971126847 @default.
- W2068258520 cites W1985876982 @default.
- W2068258520 cites W1986356875 @default.
- W2068258520 cites W1986665005 @default.
- W2068258520 cites W1988843650 @default.
- W2068258520 cites W1989957067 @default.
- W2068258520 cites W1994314618 @default.
- W2068258520 cites W1996399303 @default.
- W2068258520 cites W1996570991 @default.
- W2068258520 cites W2000370520 @default.
- W2068258520 cites W2010835536 @default.
- W2068258520 cites W2012932372 @default.
- W2068258520 cites W2023375902 @default.
- W2068258520 cites W2036225486 @default.
- W2068258520 cites W2039281520 @default.
- W2068258520 cites W2043481572 @default.
- W2068258520 cites W2047804942 @default.
- W2068258520 cites W2047923314 @default.
- W2068258520 cites W2050495774 @default.
- W2068258520 cites W2051861976 @default.
- W2068258520 cites W2055410989 @default.
- W2068258520 cites W2056141567 @default.
- W2068258520 cites W2056605430 @default.
- W2068258520 cites W2058320026 @default.
- W2068258520 cites W2059603105 @default.
- W2068258520 cites W2060008535 @default.
- W2068258520 cites W2062807619 @default.
- W2068258520 cites W2064184274 @default.
- W2068258520 cites W2077247278 @default.
- W2068258520 cites W2086217984 @default.
- W2068258520 cites W2091284527 @default.
- W2068258520 cites W2117681000 @default.
- W2068258520 cites W2120804633 @default.
- W2068258520 cites W2128625570 @default.
- W2068258520 cites W2140510132 @default.
- W2068258520 cites W2160938187 @default.
- W2068258520 cites W2161130983 @default.
- W2068258520 cites W2164704509 @default.
- W2068258520 cites W2165257280 @default.
- W2068258520 cites W2166842453 @default.
- W2068258520 cites W2168698734 @default.
- W2068258520 cites W2182032004 @default.
- W2068258520 cites W2184836824 @default.
- W2068258520 cites W2286858283 @default.
- W2068258520 cites W2307219516 @default.
- W2068258520 cites W333344667 @default.
- W2068258520 cites W4245696248 @default.
- W2068258520 doi "https://doi.org/10.1016/j.ydbio.2012.10.027" @default.
- W2068258520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23123963" @default.
- W2068258520 hasPublicationYear "2013" @default.
- W2068258520 type Work @default.
- W2068258520 sameAs 2068258520 @default.
- W2068258520 citedByCount "19" @default.
- W2068258520 countsByYear W20682585202014 @default.
- W2068258520 countsByYear W20682585202015 @default.
- W2068258520 countsByYear W20682585202016 @default.
- W2068258520 countsByYear W20682585202017 @default.
- W2068258520 countsByYear W20682585202019 @default.
- W2068258520 countsByYear W20682585202020 @default.
- W2068258520 countsByYear W20682585202021 @default.
- W2068258520 countsByYear W20682585202022 @default.
- W2068258520 countsByYear W20682585202023 @default.
- W2068258520 crossrefType "journal-article" @default.
- W2068258520 hasAuthorship W2068258520A5069467635 @default.
- W2068258520 hasAuthorship W2068258520A5071420074 @default.
- W2068258520 hasAuthorship W2068258520A5090655656 @default.
- W2068258520 hasConcept C104317684 @default.
- W2068258520 hasConcept C105702510 @default.
- W2068258520 hasConcept C113246987 @default.
- W2068258520 hasConcept C158944026 @default.
- W2068258520 hasConcept C16224149 @default.
- W2068258520 hasConcept C169760540 @default.
- W2068258520 hasConcept C190062978 @default.
- W2068258520 hasConcept C202751555 @default.
- W2068258520 hasConcept C2778944004 @default.
- W2068258520 hasConcept C2778970341 @default.
- W2068258520 hasConcept C2779530196 @default.
- W2068258520 hasConcept C54355233 @default.
- W2068258520 hasConcept C545706735 @default.
- W2068258520 hasConcept C69125201 @default.
- W2068258520 hasConcept C86803240 @default.
- W2068258520 hasConcept C91682701 @default.
- W2068258520 hasConcept C95444343 @default.