Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068273354> ?p ?o ?g. }
- W2068273354 endingPage "345" @default.
- W2068273354 startingPage "335" @default.
- W2068273354 abstract "Intrauterine growth restriction produces susceptibility to adult metabolic syndrome, which may be caused by the permanent alteration of the hypothalamic-pituitary-adrenocortical (HPA) axis. We aimed to verify that HPA axis-associated neuroendocrine metabolic programming is altered in food-restricted (FR) offspring.Maternal rats were fed a restricted diet from gestational day 11 until full-term delivery, all pups were fed a high-fat diet after weaning and exposed to unpredictable chronic stress (UCS) during postnatal weeks 17-20.Serum levels of adrenocorticotrophic hormone and corticosterone in adult offspring of the prenatal FR group were lower than the control (CN) rats before UCS but increased significantly after UCS. Serum glucose levels in the FR group were normal before UCS but increased after UCS. Serum insulin levels were significantly decreased in FR males but showed a slight increase in FR females before UCS; however, insulin levels decreased significantly in the FR male and female rats after UCS. Before UCS, serum lipid levels were higher in the FR males but were normal in the FR females; after UCS, FR males had a slight decrease and FR females had an increasing trend in serum lipids levels. Lipid droplets in the hypothalamus, pituitary gland, and livers of the FR group indicated steatosis.These results suggest that prenatal food restriction alters HPA axis-associated neuroendocrine metabolism in adult offspring fed a high-fat diet, which may originate from the intrauterine programming and increase the susceptibility to adult metabolic diseases." @default.
- W2068273354 created "2016-06-24" @default.
- W2068273354 creator A5011504904 @default.
- W2068273354 creator A5017020260 @default.
- W2068273354 creator A5029730993 @default.
- W2068273354 creator A5031756936 @default.
- W2068273354 creator A5032451346 @default.
- W2068273354 creator A5048142986 @default.
- W2068273354 creator A5066716873 @default.
- W2068273354 creator A5072904721 @default.
- W2068273354 creator A5084571872 @default.
- W2068273354 creator A5090366405 @default.
- W2068273354 date "2013-07-01" @default.
- W2068273354 modified "2023-10-18" @default.
- W2068273354 title "Prenatal Food Restriction Induces a Hypothalamic-Pituitary-Adrenocortical Axis-associated Neuroendocrine Metabolic Programmed Alteration in Adult Offspring Rats" @default.
- W2068273354 cites W1446632091 @default.
- W2068273354 cites W1496054166 @default.
- W2068273354 cites W17332004 @default.
- W2068273354 cites W183608930 @default.
- W2068273354 cites W1849290362 @default.
- W2068273354 cites W1924047294 @default.
- W2068273354 cites W1964826900 @default.
- W2068273354 cites W1969427473 @default.
- W2068273354 cites W1970294359 @default.
- W2068273354 cites W1970526904 @default.
- W2068273354 cites W1981018154 @default.
- W2068273354 cites W1981218787 @default.
- W2068273354 cites W1985222897 @default.
- W2068273354 cites W1993932990 @default.
- W2068273354 cites W2000019736 @default.
- W2068273354 cites W2001001871 @default.
- W2068273354 cites W2003801665 @default.
- W2068273354 cites W2004025901 @default.
- W2068273354 cites W2006478519 @default.
- W2068273354 cites W2006566461 @default.
- W2068273354 cites W2007037723 @default.
- W2068273354 cites W2007585598 @default.
- W2068273354 cites W2008066300 @default.
- W2068273354 cites W2013556329 @default.
- W2068273354 cites W2018393766 @default.
- W2068273354 cites W2030826355 @default.
- W2068273354 cites W2040835952 @default.
- W2068273354 cites W2041277193 @default.
- W2068273354 cites W2041524455 @default.
- W2068273354 cites W2043869076 @default.
- W2068273354 cites W2054146811 @default.
- W2068273354 cites W2054999647 @default.
- W2068273354 cites W2057795409 @default.
- W2068273354 cites W2059553551 @default.
- W2068273354 cites W2060294481 @default.
- W2068273354 cites W2061242273 @default.
- W2068273354 cites W2063437555 @default.
- W2068273354 cites W2064757899 @default.
- W2068273354 cites W2066457796 @default.
- W2068273354 cites W2071654122 @default.
- W2068273354 cites W2072363990 @default.
- W2068273354 cites W2078881833 @default.
- W2068273354 cites W2079616548 @default.
- W2068273354 cites W2083735367 @default.
- W2068273354 cites W2090917476 @default.
- W2068273354 cites W2092946739 @default.
- W2068273354 cites W2095575816 @default.
- W2068273354 cites W2097000427 @default.
- W2068273354 cites W2098777124 @default.
- W2068273354 cites W2106890297 @default.
- W2068273354 cites W2111793219 @default.
- W2068273354 cites W2112714295 @default.
- W2068273354 cites W2112761328 @default.
- W2068273354 cites W2113897100 @default.
- W2068273354 cites W2119044835 @default.
- W2068273354 cites W2119116399 @default.
- W2068273354 cites W2126108743 @default.
- W2068273354 cites W2126887647 @default.
- W2068273354 cites W2132724763 @default.
- W2068273354 cites W2135491929 @default.
- W2068273354 cites W2139109318 @default.
- W2068273354 cites W2140498210 @default.
- W2068273354 cites W2146332545 @default.
- W2068273354 cites W2148195572 @default.
- W2068273354 cites W2158594746 @default.
- W2068273354 cites W2160403269 @default.
- W2068273354 cites W2168491716 @default.
- W2068273354 cites W2170454191 @default.
- W2068273354 doi "https://doi.org/10.1016/j.arcmed.2013.07.006" @default.
- W2068273354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23911676" @default.
- W2068273354 hasPublicationYear "2013" @default.
- W2068273354 type Work @default.
- W2068273354 sameAs 2068273354 @default.
- W2068273354 citedByCount "35" @default.
- W2068273354 countsByYear W20682733542014 @default.
- W2068273354 countsByYear W20682733542015 @default.
- W2068273354 countsByYear W20682733542016 @default.
- W2068273354 countsByYear W20682733542017 @default.
- W2068273354 countsByYear W20682733542018 @default.
- W2068273354 countsByYear W20682733542019 @default.
- W2068273354 countsByYear W20682733542020 @default.
- W2068273354 countsByYear W20682733542021 @default.
- W2068273354 countsByYear W20682733542022 @default.