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- W2068274380 abstract "Metallothionein was induced in rats in response to cadmium and labeled invivo with either 109Cd, 14C or 35S. The labeled proteins were isolated from liver tissue and their metabolism was investigated after i.v. injection in rats. Tissue distribution and urinary excretion of cadmium from 109Cd-metallothionein and 109CdCl2 were different. The deposition of cadmium in kidney was higher than in liver and a significant urinary excretion of the metal was observed when administered in the form of metallothionein. In kidney and in urine 109Cd remained bound to metallothionein. The distribution and excretion of the protein moiety was very similar to that of the metal. However, gel filtration of kidney soluble fraction and urine indicated some degradation of the protein." @default.
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- W2068274380 date "1975-08-01" @default.
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- W2068274380 title "Metabolism of intravenously injected cadmium-binding protein" @default.
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- W2068274380 doi "https://doi.org/10.1016/s0006-291x(75)80465-7" @default.
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