Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068277813> ?p ?o ?g. }
- W2068277813 endingPage "111" @default.
- W2068277813 startingPage "106" @default.
- W2068277813 abstract "Heart period variability and arterial baroreceptor-cardiac reflex function were studied in cardiac transplant patients to determine if correction of heart failure restores parasympathetic control mechanisms toward normal. Heart period variability (standard deviation [SD] of 120 consecutive RR or PP intervals) was measured at supine rest in 34 patients with congestive heart failure (23 patients receiving diuretics, digoxin or vasodilators and 11 patients weaned from all medications), 30 cardiac transplant patients (both innervated recipient and denervated donor atrial rates) and 16 age-matched healthy control subjects. Arterial baroreflex gain was evaluated with intravenous bolus injections of phenylephrine in 22 transplant patients. Mean heart period variability (+/- SEM) was significantly lower (p less than 0.05) in the heart failure groups (22 +/- 3 ms for medicated and 17 +/- 3 ms for nonmedicated) than in the transplant patients (41 +/- 5 ms) or control subjects (58 +/- 5 ms). Heart period variability of the transplant patients was less than that of the control patients (p less than 0.05). A stepwise regression model revealed that heart period variability was inversely related to systolic arterial pressure and directly related to time after transplantation (R2 = 0.39; p = 0.03) in the transplant patients. Baroreflex gain of normotensive transplant patients was normal (11.7 +/- 1.0 ms/mm Hg) and correlated directly with heart period variability (r = 0.62; p less than 0.001). These data suggest that subnormal levels of cardiac parasympathetic activity at rest associated with congestive heart failure can be restored progressively toward normal by correction of congestive heart failure after cardiac transplantation. Post-transplant hypertension opposes this correction of baseline parasympathetic activity." @default.
- W2068277813 created "2016-06-24" @default.
- W2068277813 creator A5023540674 @default.
- W2068277813 creator A5028353579 @default.
- W2068277813 creator A5037623333 @default.
- W2068277813 creator A5066843009 @default.
- W2068277813 creator A5084887140 @default.
- W2068277813 date "1989-07-01" @default.
- W2068277813 modified "2023-09-27" @default.
- W2068277813 title "Subnormal heart period variability in heart failure: Effect of cardiac transplantation" @default.
- W2068277813 cites W168394801 @default.
- W2068277813 cites W1863864373 @default.
- W2068277813 cites W1965139242 @default.
- W2068277813 cites W1966946981 @default.
- W2068277813 cites W1974174134 @default.
- W2068277813 cites W1976824259 @default.
- W2068277813 cites W1980665955 @default.
- W2068277813 cites W1993665916 @default.
- W2068277813 cites W1996842876 @default.
- W2068277813 cites W2006888011 @default.
- W2068277813 cites W2022711011 @default.
- W2068277813 cites W2034562813 @default.
- W2068277813 cites W2039340624 @default.
- W2068277813 cites W2041092464 @default.
- W2068277813 cites W2042216480 @default.
- W2068277813 cites W2043157990 @default.
- W2068277813 cites W2055813262 @default.
- W2068277813 cites W2072372222 @default.
- W2068277813 cites W2142700313 @default.
- W2068277813 cites W2143540423 @default.
- W2068277813 cites W2163183941 @default.
- W2068277813 cites W2336832375 @default.
- W2068277813 cites W2338638760 @default.
- W2068277813 cites W2397861434 @default.
- W2068277813 cites W2413741986 @default.
- W2068277813 cites W2414407708 @default.
- W2068277813 cites W2471878425 @default.
- W2068277813 doi "https://doi.org/10.1016/0735-1097(89)90059-4" @default.
- W2068277813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2661625" @default.
- W2068277813 hasPublicationYear "1989" @default.
- W2068277813 type Work @default.
- W2068277813 sameAs 2068277813 @default.
- W2068277813 citedByCount "32" @default.
- W2068277813 countsByYear W20682778132012 @default.
- W2068277813 countsByYear W20682778132020 @default.
- W2068277813 crossrefType "journal-article" @default.
- W2068277813 hasAuthorship W2068277813A5023540674 @default.
- W2068277813 hasAuthorship W2068277813A5028353579 @default.
- W2068277813 hasAuthorship W2068277813A5037623333 @default.
- W2068277813 hasAuthorship W2068277813A5066843009 @default.
- W2068277813 hasAuthorship W2068277813A5084887140 @default.
- W2068277813 hasBestOaLocation W20682778131 @default.
- W2068277813 hasConcept C111566952 @default.
- W2068277813 hasConcept C125567185 @default.
- W2068277813 hasConcept C126322002 @default.
- W2068277813 hasConcept C139940330 @default.
- W2068277813 hasConcept C164705383 @default.
- W2068277813 hasConcept C191237925 @default.
- W2068277813 hasConcept C2777707475 @default.
- W2068277813 hasConcept C2777953023 @default.
- W2068277813 hasConcept C2778198053 @default.
- W2068277813 hasConcept C2778849806 @default.
- W2068277813 hasConcept C2911091166 @default.
- W2068277813 hasConcept C42219234 @default.
- W2068277813 hasConcept C71924100 @default.
- W2068277813 hasConcept C79752029 @default.
- W2068277813 hasConcept C84393581 @default.
- W2068277813 hasConceptScore W2068277813C111566952 @default.
- W2068277813 hasConceptScore W2068277813C125567185 @default.
- W2068277813 hasConceptScore W2068277813C126322002 @default.
- W2068277813 hasConceptScore W2068277813C139940330 @default.
- W2068277813 hasConceptScore W2068277813C164705383 @default.
- W2068277813 hasConceptScore W2068277813C191237925 @default.
- W2068277813 hasConceptScore W2068277813C2777707475 @default.
- W2068277813 hasConceptScore W2068277813C2777953023 @default.
- W2068277813 hasConceptScore W2068277813C2778198053 @default.
- W2068277813 hasConceptScore W2068277813C2778849806 @default.
- W2068277813 hasConceptScore W2068277813C2911091166 @default.
- W2068277813 hasConceptScore W2068277813C42219234 @default.
- W2068277813 hasConceptScore W2068277813C71924100 @default.
- W2068277813 hasConceptScore W2068277813C79752029 @default.
- W2068277813 hasConceptScore W2068277813C84393581 @default.
- W2068277813 hasIssue "1" @default.
- W2068277813 hasLocation W20682778131 @default.
- W2068277813 hasLocation W20682778132 @default.
- W2068277813 hasOpenAccess W2068277813 @default.
- W2068277813 hasPrimaryLocation W20682778131 @default.
- W2068277813 hasRelatedWork W1963535343 @default.
- W2068277813 hasRelatedWork W1975155699 @default.
- W2068277813 hasRelatedWork W2116320226 @default.
- W2068277813 hasRelatedWork W2126501164 @default.
- W2068277813 hasRelatedWork W2149186415 @default.
- W2068277813 hasRelatedWork W2151321443 @default.
- W2068277813 hasRelatedWork W2772042074 @default.
- W2068277813 hasRelatedWork W3082743643 @default.
- W2068277813 hasRelatedWork W3185290845 @default.
- W2068277813 hasRelatedWork W4211195567 @default.
- W2068277813 hasVolume "14" @default.