Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068287872> ?p ?o ?g. }
- W2068287872 endingPage "1289" @default.
- W2068287872 startingPage "1281" @default.
- W2068287872 abstract "Evidence suggests that individuals with posttraumatic stress disorder (PTSD) have an enhanced sensitization of the hypothalamic--pituitary--adrenocortical (HPA) axis. However, few studies in adolescents have been performed. Fourteen sexually abused adolescent inpatients with DSM-IV PTSD (12 female, two male; mean +/- SD age, 16.2 +/- 1.9 years) were compared with 14 adolescent hospitalized controls (11 female, three male; mean age, 15.7 +/- 2.0 years). All subjects underwent a standard dexamethasone suppression test (DST, 1 mg given orally at 2300 h) five days after admission. Baseline blood samples were obtained at 0800 h, and the following day, adrenocorticotropin (ACTH) and cortisol levels were measured at 0800, 1600, and 2300 h. Clinical assessment included the Impact of Event Scale, Stanford Acute Stress Reaction Questionnaire, Beck Depression Inventory, and Coping Inventory for Stressful Situations. Post-DST ACTH levels were significantly lower in PTSD than in control adolescents (at 0800 h: P < 0.005; at 1600 h: P < 0.001; at 2300 h: P < 0.05). In patients, post-DST cortisol levels were reduced but not significantly. No correlations were found between ACTH and cortisol levels and time elapsed since trauma. These results demonstrate that sexually abused adolescents with PTSD show ACTH hypersuppression to DST suggesting enhanced glucocorticoid receptor sensitivity in the pituitary." @default.
- W2068287872 created "2016-06-24" @default.
- W2068287872 creator A5025152015 @default.
- W2068287872 creator A5038141140 @default.
- W2068287872 creator A5048383270 @default.
- W2068287872 creator A5053747914 @default.
- W2068287872 creator A5068617244 @default.
- W2068287872 creator A5073670285 @default.
- W2068287872 creator A5078409600 @default.
- W2068287872 date "2004-11-01" @default.
- W2068287872 modified "2023-10-17" @default.
- W2068287872 title "Increased adrenocorticotropin suppression following dexamethasone administration in sexually abused adolescents with posttraumatic stress disorder*1" @default.
- W2068287872 cites W141444043 @default.
- W2068287872 cites W1536317835 @default.
- W2068287872 cites W1550462067 @default.
- W2068287872 cites W1578409595 @default.
- W2068287872 cites W1746209842 @default.
- W2068287872 cites W1794165588 @default.
- W2068287872 cites W1802833855 @default.
- W2068287872 cites W1849143904 @default.
- W2068287872 cites W1897310022 @default.
- W2068287872 cites W1965376635 @default.
- W2068287872 cites W1976735983 @default.
- W2068287872 cites W1986182757 @default.
- W2068287872 cites W1991047926 @default.
- W2068287872 cites W1992582497 @default.
- W2068287872 cites W1999036268 @default.
- W2068287872 cites W1999218524 @default.
- W2068287872 cites W2005381078 @default.
- W2068287872 cites W2009637266 @default.
- W2068287872 cites W2015219993 @default.
- W2068287872 cites W2017034268 @default.
- W2068287872 cites W2019395223 @default.
- W2068287872 cites W2021471819 @default.
- W2068287872 cites W2028056159 @default.
- W2068287872 cites W2031041075 @default.
- W2068287872 cites W2036151629 @default.
- W2068287872 cites W2036396063 @default.
- W2068287872 cites W2049744963 @default.
- W2068287872 cites W2054229769 @default.
- W2068287872 cites W2055161357 @default.
- W2068287872 cites W2065263467 @default.
- W2068287872 cites W2066358461 @default.
- W2068287872 cites W2067495470 @default.
- W2068287872 cites W2071057820 @default.
- W2068287872 cites W2073376147 @default.
- W2068287872 cites W2077017047 @default.
- W2068287872 cites W2077666777 @default.
- W2068287872 cites W2082574777 @default.
- W2068287872 cites W2094311581 @default.
- W2068287872 cites W2103924188 @default.
- W2068287872 cites W2112247320 @default.
- W2068287872 cites W2113232110 @default.
- W2068287872 cites W2114613490 @default.
- W2068287872 cites W2136800716 @default.
- W2068287872 cites W2145161166 @default.
- W2068287872 cites W2147439730 @default.
- W2068287872 cites W2159011576 @default.
- W2068287872 cites W2160070901 @default.
- W2068287872 cites W2171132931 @default.
- W2068287872 cites W2171342470 @default.
- W2068287872 cites W2180340478 @default.
- W2068287872 cites W2219191873 @default.
- W2068287872 cites W2406895737 @default.
- W2068287872 cites W2430202101 @default.
- W2068287872 cites W2469628954 @default.
- W2068287872 cites W253326700 @default.
- W2068287872 cites W3200160465 @default.
- W2068287872 doi "https://doi.org/10.1016/j.psyneuen.2004.03.006" @default.
- W2068287872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15288707" @default.
- W2068287872 hasPublicationYear "2004" @default.
- W2068287872 type Work @default.
- W2068287872 sameAs 2068287872 @default.
- W2068287872 citedByCount "50" @default.
- W2068287872 countsByYear W20682878722012 @default.
- W2068287872 countsByYear W20682878722013 @default.
- W2068287872 countsByYear W20682878722014 @default.
- W2068287872 countsByYear W20682878722015 @default.
- W2068287872 countsByYear W20682878722016 @default.
- W2068287872 countsByYear W20682878722017 @default.
- W2068287872 countsByYear W20682878722019 @default.
- W2068287872 countsByYear W20682878722020 @default.
- W2068287872 countsByYear W20682878722021 @default.
- W2068287872 countsByYear W20682878722022 @default.
- W2068287872 countsByYear W20682878722023 @default.
- W2068287872 crossrefType "journal-article" @default.
- W2068287872 hasAuthorship W2068287872A5025152015 @default.
- W2068287872 hasAuthorship W2068287872A5038141140 @default.
- W2068287872 hasAuthorship W2068287872A5048383270 @default.
- W2068287872 hasAuthorship W2068287872A5053747914 @default.
- W2068287872 hasAuthorship W2068287872A5068617244 @default.
- W2068287872 hasAuthorship W2068287872A5073670285 @default.
- W2068287872 hasAuthorship W2068287872A5078409600 @default.
- W2068287872 hasConcept C118552586 @default.
- W2068287872 hasConcept C126322002 @default.
- W2068287872 hasConcept C134018914 @default.
- W2068287872 hasConcept C139719470 @default.
- W2068287872 hasConcept C15744967 @default.