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- W2068289325 abstract "Homozygous carriers of a haplotype consisting of ERCC1 Asn118AsnA, ASE-1 G-21AG, RAI IVS1 A4364GA are at increased risk of lung cancer especially among women. Here, we analyse for gene-environment interactions with the predefined haplotype in a case cohort study including 428 lung cancer cases and a comparison group of 800 persons, all from the prospective Diet, Cancer and Health cohort of 57,000 Danes. At high smoking intensity (>20 g tobacco/day), there was only additional risk of smoking intensity among women who were homozygous carriers of the haplotype (IRR=2.03; 95% CI: 1.10–3.73 per 5 additional g tobacco/day)." @default.
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- W2068289325 date "2007-03-01" @default.
- W2068289325 modified "2023-10-10" @default.
- W2068289325 title "Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study" @default.
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- W2068289325 doi "https://doi.org/10.1016/j.canlet.2006.04.001" @default.
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