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- W2068291431 abstract "The methanolic extract from the seeds of Psoralea corylifolia was found to inhibit production of nitric oxide (NO) in lipopolysaccharide-activated mouse peritoneal macrophages. Among the isolated compounds, bavachinin (IC50=26 μM), isobavachalcone (17 μM), neobavaisoflavone (ca. 29 μM), corylifol A (ca. 21 μM), and psoralidin (ca. 23 μM) significantly inhibited the accumulation of nitrite (NO2−) as a marker of production of NO. Bakuchiol, which is mainly contained in the extract, also showed weak activity at 10 μM, but cytotoxic effects were observed more than 30 μM." @default.
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- W2068291431 date "2009-01-01" @default.
- W2068291431 modified "2023-10-18" @default.
- W2068291431 title "Bioactive Constituents from Chinese Natural Medicines. XXXIII. Inhibitors from the Seeds of Psoralea corylifolia on Production of Nitric Oxide in Lipopolysaccharide-Activated Macrophages" @default.
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- W2068291431 doi "https://doi.org/10.1248/bpb.32.147" @default.
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