FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068313458> ?p ?o ?g. }

• W2068313458 endingPage "1710" @default.
• W2068313458 startingPage "1703" @default.
• W2068313458 abstract "A method was developed to prepare 5′-deoxy-5′-substituted-ψ-uridine derivatives 4 from 3′,5′-O-(1, 1, 3, 3-tetraisopropyldisiloxanyl)-1,3-dimethyl-ψ-uridine 1 via a silyl rearrangement reaction. Nucleophilic displacement of the mesyloxy function of 2′-O-mesyl-1,3-dimethyl-ψ-uridine 7 afforded products with the 2′-substituent in the “down” ribo configuration 8. X-Ray crystallographic analysis of the 2′-chloro derivative 8a firmly established the molecular structure of 8 and provided evidence for neighboring group participation of the 4-carbonyl function of 7 during the nucleophilic reactions. Treatment of 1,3-dimethyl-ψ-uridine 11 with α-acetoxyisobutyryl chloride afforded a mixture from which two 2′-chloro-2′-deoxy-C-nucleosides were obtained. The major product (33% yield) was identical with 8. The minor product (7% yield) was consequently assigned the arabino nucleoside 14. This is the first direct introduction of a 2′-substituent in the “up” configuration in a preformed pyrimidine nucleoside." @default.
• W2068313458 created "2016-06-24" @default.
• W2068313458 creator A5006468881 @default.
• W2068313458 creator A5013760358 @default.
• W2068313458 creator A5027078344 @default.
• W2068313458 creator A5043214204 @default.
• W2068313458 creator A5085675134 @default.
• W2068313458 date "1985-11-01" @default.
• W2068313458 modified "2023-09-23" @default.
• W2068313458 title "Nucleosides.<b>130</b>. Synthesis of 2′-Deoxy-2′-substituted- and 5′-Deoxy-5′-substituted-ψ-uridine Derivatives. Crystalline and Molecular Structure of 2′-Chloro-2′-deoxy-1,3-dimethyl-ψ-uridine. Studies Directed Toward the Synthesis of 2′-Deoxy-2′-substituted-<i>arabino</i>-Nucleosides.<b>1</b>" @default.
• W2068313458 cites W136156762 @default.
• W2068313458 cites W1970821982 @default.
• W2068313458 cites W1973606133 @default.
• W2068313458 cites W1982618646 @default.
• W2068313458 cites W1984659682 @default.
• W2068313458 cites W1984897569 @default.
• W2068313458 cites W1995626688 @default.
• W2068313458 cites W2006386873 @default.
• W2068313458 cites W2018779204 @default.
• W2068313458 cites W2042933997 @default.
• W2068313458 cites W2048649930 @default.
• W2068313458 cites W2049850818 @default.
• W2068313458 cites W2064921951 @default.
• W2068313458 cites W2070431527 @default.
• W2068313458 cites W2072081893 @default.
• W2068313458 cites W2073614125 @default.
• W2068313458 cites W2076302128 @default.
• W2068313458 cites W2090062000 @default.
• W2068313458 cites W2094811518 @default.
• W2068313458 cites W2342611038 @default.
• W2068313458 cites W2950157222 @default.
• W2068313458 doi "https://doi.org/10.1002/jhet.5570220646" @default.
• W2068313458 hasPublicationYear "1985" @default.
• W2068313458 type Work @default.
• W2068313458 sameAs 2068313458 @default.
• W2068313458 citedByCount "13" @default.
• W2068313458 countsByYear W20683134582020 @default.
• W2068313458 crossrefType "journal-article" @default.
• W2068313458 hasAuthorship W2068313458A5006468881 @default.
• W2068313458 hasAuthorship W2068313458A5013760358 @default.
• W2068313458 hasAuthorship W2068313458A5027078344 @default.
• W2068313458 hasAuthorship W2068313458A5043214204 @default.
• W2068313458 hasAuthorship W2068313458A5085675134 @default.
• W2068313458 hasConcept C104317684 @default.
• W2068313458 hasConcept C106159729 @default.
• W2068313458 hasConcept C111771559 @default.
• W2068313458 hasConcept C134121241 @default.
• W2068313458 hasConcept C161790260 @default.
• W2068313458 hasConcept C162324750 @default.
• W2068313458 hasConcept C178790620 @default.
• W2068313458 hasConcept C178907741 @default.
• W2068313458 hasConcept C185592680 @default.
• W2068313458 hasConcept C191897082 @default.
• W2068313458 hasConcept C192562407 @default.
• W2068313458 hasConcept C2776543447 @default.
• W2068313458 hasConcept C2778689049 @default.
• W2068313458 hasConcept C2779321679 @default.
• W2068313458 hasConcept C2781259782 @default.
• W2068313458 hasConcept C5304478 @default.
• W2068313458 hasConcept C55493867 @default.
• W2068313458 hasConcept C67705224 @default.
• W2068313458 hasConcept C71240020 @default.
• W2068313458 hasConceptScore W2068313458C104317684 @default.
• W2068313458 hasConceptScore W2068313458C106159729 @default.
• W2068313458 hasConceptScore W2068313458C111771559 @default.
• W2068313458 hasConceptScore W2068313458C134121241 @default.
• W2068313458 hasConceptScore W2068313458C161790260 @default.
• W2068313458 hasConceptScore W2068313458C162324750 @default.
• W2068313458 hasConceptScore W2068313458C178790620 @default.
• W2068313458 hasConceptScore W2068313458C178907741 @default.
• W2068313458 hasConceptScore W2068313458C185592680 @default.
• W2068313458 hasConceptScore W2068313458C191897082 @default.
• W2068313458 hasConceptScore W2068313458C192562407 @default.
• W2068313458 hasConceptScore W2068313458C2776543447 @default.
• W2068313458 hasConceptScore W2068313458C2778689049 @default.
• W2068313458 hasConceptScore W2068313458C2779321679 @default.
• W2068313458 hasConceptScore W2068313458C2781259782 @default.
• W2068313458 hasConceptScore W2068313458C5304478 @default.
• W2068313458 hasConceptScore W2068313458C55493867 @default.
• W2068313458 hasConceptScore W2068313458C67705224 @default.
• W2068313458 hasConceptScore W2068313458C71240020 @default.
• W2068313458 hasIssue "6" @default.
• W2068313458 hasLocation W20683134581 @default.
• W2068313458 hasOpenAccess W2068313458 @default.
• W2068313458 hasPrimaryLocation W20683134581 @default.
• W2068313458 hasRelatedWork W1803328452 @default.
• W2068313458 hasRelatedWork W1976250883 @default.
• W2068313458 hasRelatedWork W2056351602 @default.
• W2068313458 hasRelatedWork W2068313458 @default.
• W2068313458 hasRelatedWork W2087570138 @default.
• W2068313458 hasRelatedWork W2322413980 @default.
• W2068313458 hasRelatedWork W2521607463 @default.
• W2068313458 hasRelatedWork W2949730139 @default.
• W2068313458 hasRelatedWork W2951501242 @default.
• W2068313458 hasRelatedWork W627971866 @default.
• W2068313458 hasVolume "22" @default.
• W2068313458 isParatext "false" @default.
• W2068313458 isRetracted "false" @default.

• next