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- W2068331366 abstract "Asthma is a chronic airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction. Airway structural changes or airway remodelling consist of epithelial injury, goblet cell hyperplasia, subepithelial layer thickening, airway smooth muscle hyperplasia and angiogenesis. These changes were previously considered as a consequence of chronic airway inflammation. Even though inhaled corticosteroids can suppress airway inflammation, the natural history of asthma is still unaltered after inhaled corticosteroid treatment. As such there is increasing evidence for the role of mechanical forces within the asthmatic airway contributing to airway structural changes." @default.
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- W2068331366 date "2014-01-01" @default.
- W2068331366 modified "2023-10-06" @default.
- W2068331366 title "Airway remodelling in asthma: role for mechanical forces" @default.
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- W2068331366 doi "https://doi.org/10.5415/apallergy.2014.4.1.19" @default.
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