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- W2068347992 abstract "In coeliac disease, gluten, or one of its fractions, combines with a gut-wall macrophage or lymphocyte to form a lymphoid cell which is recognised by the host as foreign. It is proposed that this cell, rather than being eliminated as the target of a cell-mediated attack by the host, becomes autonomous and initiates a graft-versus-host (GvH)-like reaction. The reaction is largely confined to the gut wall and its associated lymphoid tissue. The severe cachexy and the peripheral lymph-node and splenic atrophy may be explained as features of chronic GvH disease. or a runting syndrome. Untreated coeliac disease may lead to lymphomatous transformation indistinguishable from the lymphoma of experimental chronic GvH disease" @default.
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- W2068347992 date "1981-04-01" @default.
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- W2068347992 title "COELIAC DISEASE: A GRAFT-VERSUS-HOST-LIKE REACTION LOCALISED TO THE SMALL BOWEL WALL?" @default.
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- W2068347992 doi "https://doi.org/10.1016/s0140-6736(81)92683-0" @default.
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