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- W2068358049 abstract "Since Edward Jenners discovery of the basic concept of vaccination in 1796 vaccines have become a critical component of our armamentarium for preventing a broad spectrum of infectious diseases. Vaccination now sits at center stage in our ability to impact public health on a global scale and aside from sanitation and clean water represents one of the easiest and most cost-effective means to control infectious diseases and improve people s standards of life. The beneficial impact of vaccination extends beyond protection of the individual - so it gives rise to herd immunity an effect whereby vaccination of a large proportion of the population hinders the transmission of an infectious agent and thereby protects the entire population even those not vaccinated. Indeed this effect has led to some remarkable results including eradication of smallpox and virtual disappearance of diphtheria tetanus and paralytic poliomyelitis. However it is clear that much remains to be accomplished to close the global vaccination gap and to reduce the annual toll of approximately 3 million children dying from vaccine-preventable diseases. (excerpt)" @default.
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- W2068358049 date "2007-12-01" @default.
- W2068358049 modified "2023-09-26" @default.
- W2068358049 title "Vaccines at the turn of the 21st century: a new era for immunization in public health" @default.
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- W2068358049 doi "https://doi.org/10.1016/s1201-9712(07)60014-9" @default.
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