Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068365329> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2068365329 endingPage "455" @default.
- W2068365329 startingPage "451" @default.
- W2068365329 abstract "Mammalian genomes are partitioned in chromosomes and contain millions of base pairs that encode for tens of thousands of protein-coding genes ( approximately 30,000 in humans) and many more non-coding transcripts. Gene forests interspersed with gene deserts in the linear DNA sequence may segregate into domains that are more or less permissive for transcription within the three-dimensional nucleus. Functional attachments to various nuclear landmarks are thought to organise the architectural folding of the chromosome fibre. The position of a gene within the nucleus can favour its silencing or activation and the efficiency with which its products are processed or transported to the cytoplasm. The stochastic properties of genome organisation may contribute to cell-type-specific gene expression and to the dynamic responses that occur during differentiation and adaptation to the environment. The first steps for high-throughput mapping of chromosome architecture in specific cell types are under way to help understand the mechanisms by which genome architecture may regulate gene expression." @default.
- W2068365329 created "2016-06-24" @default.
- W2068365329 creator A5070136083 @default.
- W2068365329 creator A5086859882 @default.
- W2068365329 date "2007-10-01" @default.
- W2068365329 modified "2023-10-17" @default.
- W2068365329 title "Functional organisation of the genome during interphase" @default.
- W2068365329 cites W1972516690 @default.
- W2068365329 cites W1990396035 @default.
- W2068365329 cites W1991149014 @default.
- W2068365329 cites W1992040206 @default.
- W2068365329 cites W1999155341 @default.
- W2068365329 cites W2010295908 @default.
- W2068365329 cites W2019666363 @default.
- W2068365329 cites W2020977773 @default.
- W2068365329 cites W2026180423 @default.
- W2068365329 cites W2032840484 @default.
- W2068365329 cites W2040544622 @default.
- W2068365329 cites W2041159570 @default.
- W2068365329 cites W2047734673 @default.
- W2068365329 cites W2056422973 @default.
- W2068365329 cites W2057087360 @default.
- W2068365329 cites W2057341073 @default.
- W2068365329 cites W2061015334 @default.
- W2068365329 cites W2077154575 @default.
- W2068365329 cites W2089894746 @default.
- W2068365329 cites W2092499706 @default.
- W2068365329 cites W2103250022 @default.
- W2068365329 cites W2109264912 @default.
- W2068365329 cites W2110358117 @default.
- W2068365329 cites W2111012767 @default.
- W2068365329 cites W2114129635 @default.
- W2068365329 cites W2122887139 @default.
- W2068365329 cites W2137940450 @default.
- W2068365329 cites W2144660247 @default.
- W2068365329 cites W2153161471 @default.
- W2068365329 cites W2155837532 @default.
- W2068365329 cites W2162219284 @default.
- W2068365329 cites W2166062110 @default.
- W2068365329 cites W2168857762 @default.
- W2068365329 cites W2170725825 @default.
- W2068365329 cites W2171393347 @default.
- W2068365329 doi "https://doi.org/10.1016/j.gde.2007.08.008" @default.
- W2068365329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17920259" @default.
- W2068365329 hasPublicationYear "2007" @default.
- W2068365329 type Work @default.
- W2068365329 sameAs 2068365329 @default.
- W2068365329 citedByCount "50" @default.
- W2068365329 countsByYear W20683653292012 @default.
- W2068365329 countsByYear W20683653292013 @default.
- W2068365329 countsByYear W20683653292014 @default.
- W2068365329 countsByYear W20683653292015 @default.
- W2068365329 countsByYear W20683653292016 @default.
- W2068365329 countsByYear W20683653292017 @default.
- W2068365329 countsByYear W20683653292019 @default.
- W2068365329 countsByYear W20683653292022 @default.
- W2068365329 countsByYear W20683653292023 @default.
- W2068365329 crossrefType "journal-article" @default.
- W2068365329 hasAuthorship W2068365329A5070136083 @default.
- W2068365329 hasAuthorship W2068365329A5086859882 @default.
- W2068365329 hasConcept C104317684 @default.
- W2068365329 hasConcept C141231307 @default.
- W2068365329 hasConcept C22322919 @default.
- W2068365329 hasConcept C54355233 @default.
- W2068365329 hasConcept C66746571 @default.
- W2068365329 hasConcept C70721500 @default.
- W2068365329 hasConcept C86803240 @default.
- W2068365329 hasConceptScore W2068365329C104317684 @default.
- W2068365329 hasConceptScore W2068365329C141231307 @default.
- W2068365329 hasConceptScore W2068365329C22322919 @default.
- W2068365329 hasConceptScore W2068365329C54355233 @default.
- W2068365329 hasConceptScore W2068365329C66746571 @default.
- W2068365329 hasConceptScore W2068365329C70721500 @default.
- W2068365329 hasConceptScore W2068365329C86803240 @default.
- W2068365329 hasIssue "5" @default.
- W2068365329 hasLocation W20683653291 @default.
- W2068365329 hasLocation W20683653292 @default.
- W2068365329 hasOpenAccess W2068365329 @default.
- W2068365329 hasPrimaryLocation W20683653291 @default.
- W2068365329 hasRelatedWork W114861936 @default.
- W2068365329 hasRelatedWork W1491897707 @default.
- W2068365329 hasRelatedWork W1638089104 @default.
- W2068365329 hasRelatedWork W1974297084 @default.
- W2068365329 hasRelatedWork W1993011193 @default.
- W2068365329 hasRelatedWork W2011383889 @default.
- W2068365329 hasRelatedWork W2022454203 @default.
- W2068365329 hasRelatedWork W2046367246 @default.
- W2068365329 hasRelatedWork W2987420353 @default.
- W2068365329 hasRelatedWork W1974981762 @default.
- W2068365329 hasVolume "17" @default.
- W2068365329 isParatext "false" @default.
- W2068365329 isRetracted "false" @default.
- W2068365329 magId "2068365329" @default.
- W2068365329 workType "article" @default.