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- W2068374464 abstract "Oral administration of 7α-methyl-19-nortestosterone 17-(1-adamantoate) (MNTA) to 2 groups of castrated male rabbits exhibiting no sexual activity was started at daily doses of 3 and 1 mg per kg of body weight, respectively. Similarly, 17α-methyl-androst-4-ene-17β-ol-3-one (17α-methyl testosterone, or MT) was administered at doses of 6 and 2 mg per kg body weight, respectively. Sexual behavior was observed 15 times per week during 5 weeks of treatment. Data confirmed the oral activity of these compounds in restoring sexual activity. Animals treated with 3 mg MNTA and 6 mg MT attained 50% of their recovery in approximately 2 weeks and 4 weeks, respectively. An oral potency of MNTA in respect to stimulation of sexual activity was calculated to be 3.4 times MT, with 95% confidence limits of 2.6–4.2" @default.
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- W2068374464 date "1973-12-01" @default.
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- W2068374464 title "Sexual activity in castrated male rabbits after oral administration of 7 α-methyl-19-nortestosterone 17-(1-adamantoate)" @default.
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- W2068374464 doi "https://doi.org/10.1016/0031-9384(73)90287-4" @default.
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