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- W2068378515 abstract "Treatment of pregnant rats with heat-denaturated bacterial material (endotoxin-model) or exposure to chronic restraint of prenatally lithium-treated pregnant dams (stress-model) were used as two models of disturbed pregnancy, both causing decreased fetal body mass. The quotient of fetal/placental mass was lowered in the endotoxin-group only. Placental mass and protein content were not changed significantly in both experimental groups, although a tendency to smaller placentae was noticed in the stress-group. Placental histology of the stress-group did not differ from untreated controls. In the endotoxin-group an altered structure of the placental barrier was observed. Small decreases of GSH and GSSG in the endotoxin-group and of GSSG in the stress-group without significant changes of the GSH/GSSG relationship were measured in homogenates of the placental labyrinth. Moderate enhancement of LPO concentration occurred in the endotoxin-group and more distinctly in two litters of the stress-group, the latter being connected with high GSSG concentrations and low fetal/placental mass-quotients." @default.
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- W2068378515 date "1992-01-01" @default.
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- W2068378515 title "Placental morphology and concentrations of glutathione (GSH and GSSG) and lipid peroxides (LPO) in two models of disturbed pregnancy of Uje:WIST rats" @default.
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- W2068378515 doi "https://doi.org/10.1016/s0940-2993(11)80249-6" @default.
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