FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068387575> ?p ?o ?g. }

• W2068387575 endingPage "14637" @default.
• W2068387575 startingPage "14632" @default.
• W2068387575 abstract "Cranial radiation therapy is commonly used in the treatment of childhood cancers. It is associated with cognitive impairments tentatively linked to the hippocampus, a neurogenic region of the brain important in memory function and learning. Hippocampal neurogenesis is positively regulated by voluntary exercise, which is also known to improve hippocampal-dependent cognitive functions. In this work, we irradiated the brains of C57/BL6 mice on postnatal day 9 and evaluated both the acute effects of irradiation and the effects of voluntary running on hippocampal neurogenesis and behavior 3 months after irradiation. Voluntary running significantly restored precursor cell and neurogenesis levels after a clinically relevant, moderate dose of irradiation. We also found that irradiation perturbed the structural integration of immature neurons in the hippocampus and that this was reversed by voluntary exercise. Furthermore, irradiation-induced behavior alterations observed in the open-field test were ameliorated. Together, these results clearly demonstrate the usefulness of physical exercise for functional and structural recovery from radiation-induced injury to the juvenile brain, and they suggest that exercise should be evaluated in rehabilitation therapy of childhood cancer survivors." @default.
• W2068387575 created "2016-06-24" @default.
• W2068387575 creator A5015124486 @default.
• W2068387575 creator A5018235024 @default.
• W2068387575 creator A5021905275 @default.
• W2068387575 creator A5035240366 @default.
• W2068387575 creator A5039742852 @default.
• W2068387575 creator A5065124171 @default.
• W2068387575 creator A5067177483 @default.
• W2068387575 creator A5068054602 @default.
• W2068387575 date "2008-09-23" @default.
• W2068387575 modified "2023-10-11" @default.
• W2068387575 title "Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain" @default.
• W2068387575 cites W1963940970 @default.
• W2068387575 cites W1964293607 @default.
• W2068387575 cites W1968660144 @default.
• W2068387575 cites W1970330769 @default.
• W2068387575 cites W1970516662 @default.
• W2068387575 cites W1971747664 @default.
• W2068387575 cites W1981279518 @default.
• W2068387575 cites W1984948341 @default.
• W2068387575 cites W1986346910 @default.
• W2068387575 cites W1995188451 @default.
• W2068387575 cites W1995341268 @default.
• W2068387575 cites W1999927211 @default.
• W2068387575 cites W2006023953 @default.
• W2068387575 cites W2007095775 @default.
• W2068387575 cites W2012403948 @default.
• W2068387575 cites W2021461047 @default.
• W2068387575 cites W2021551531 @default.
• W2068387575 cites W2025288365 @default.
• W2068387575 cites W2025604203 @default.
• W2068387575 cites W2029673224 @default.
• W2068387575 cites W2031087975 @default.
• W2068387575 cites W2033736131 @default.
• W2068387575 cites W2041243237 @default.
• W2068387575 cites W2043204105 @default.
• W2068387575 cites W2048546110 @default.
• W2068387575 cites W2051228574 @default.
• W2068387575 cites W2054113947 @default.
• W2068387575 cites W2067660712 @default.
• W2068387575 cites W2067856703 @default.
• W2068387575 cites W2069308124 @default.
• W2068387575 cites W2070444599 @default.
• W2068387575 cites W2070794162 @default.
• W2068387575 cites W2071181288 @default.
• W2068387575 cites W2075894364 @default.
• W2068387575 cites W2079959894 @default.
• W2068387575 cites W2083536310 @default.
• W2068387575 cites W2083743152 @default.
• W2068387575 cites W2089394861 @default.
• W2068387575 cites W2092245844 @default.
• W2068387575 cites W2098137179 @default.
• W2068387575 cites W2099250398 @default.
• W2068387575 cites W2100011555 @default.
• W2068387575 cites W2107501599 @default.
• W2068387575 cites W2112977759 @default.
• W2068387575 cites W2119757776 @default.
• W2068387575 cites W2122586715 @default.
• W2068387575 cites W2140769712 @default.
• W2068387575 cites W2142525943 @default.
• W2068387575 cites W2145235967 @default.
• W2068387575 cites W2145884075 @default.
• W2068387575 cites W2145944042 @default.
• W2068387575 cites W2147162709 @default.
• W2068387575 cites W2148099028 @default.
• W2068387575 cites W2148842308 @default.
• W2068387575 cites W2149102473 @default.
• W2068387575 cites W2152794331 @default.
• W2068387575 cites W2152820394 @default.
• W2068387575 cites W2153533547 @default.
• W2068387575 cites W2158628168 @default.
• W2068387575 cites W2166192872 @default.
• W2068387575 cites W4245559451 @default.
• W2068387575 doi "https://doi.org/10.1073/pnas.0711128105" @default.
• W2068387575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2567198" @default.
• W2068387575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18765809" @default.
• W2068387575 hasPublicationYear "2008" @default.
• W2068387575 type Work @default.
• W2068387575 sameAs 2068387575 @default.
• W2068387575 citedByCount "190" @default.
• W2068387575 countsByYear W20683875752012 @default.
• W2068387575 countsByYear W20683875752013 @default.
• W2068387575 countsByYear W20683875752014 @default.
• W2068387575 countsByYear W20683875752015 @default.
• W2068387575 countsByYear W20683875752016 @default.
• W2068387575 countsByYear W20683875752017 @default.
• W2068387575 countsByYear W20683875752018 @default.
• W2068387575 countsByYear W20683875752019 @default.
• W2068387575 countsByYear W20683875752020 @default.
• W2068387575 countsByYear W20683875752021 @default.
• W2068387575 countsByYear W20683875752022 @default.
• W2068387575 countsByYear W20683875752023 @default.
• W2068387575 crossrefType "journal-article" @default.
• W2068387575 hasAuthorship W2068387575A5015124486 @default.
• W2068387575 hasAuthorship W2068387575A5018235024 @default.
• W2068387575 hasAuthorship W2068387575A5021905275 @default.
• W2068387575 hasAuthorship W2068387575A5035240366 @default.

• next