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- W2068388785 abstract "A penicillin-induced, epileptogenic focus within the boundaries of chronically isolated cortex of cats could be activated to discharge regularly by intra-muscular administration of pentylenetetrazol. A sensory-sensory conditioning procedure was used to establish temporary connections between a sensory stimulus and these paroxysmal discharges. When a tone was repeatedly paired with a flickering light, it increasingly acquired the property of inhibiting the spike discharges. Another tone, which was not paired with the light, did not show the conditioned inhibition. The shifts of cortical steady potentials evoked by the conditional, unconditional, and differential stimuli, were not correlated with the conditioning process. Polarization with direct current up to 500 μA did not affect the penicillin spikes. The possible mechanisms involved in the conditioned inhibition of the penicillin spikes inside an isolated slab, and the relevance of the present results to neural mechanisms of learning are discussed." @default.
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- W2068388785 date "1964-11-01" @default.
- W2068388785 modified "2023-10-18" @default.
- W2068388785 title "Bioelectrical activity of isolated cortex—III conditioned electrographic responses in chronically isolated cortex" @default.
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- W2068388785 doi "https://doi.org/10.1016/0028-3932(64)90003-x" @default.
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