FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068420983> ?p ?o ?g. }

• W2068420983 endingPage "1120" @default.
• W2068420983 startingPage "1111" @default.
• W2068420983 abstract "Biomarkers and image markers of Alzheimer's disease (AD), such as cerebrospinal fluid Aβ42 and p-tau, are effective predictors of cognitive decline or dementia. The aim of this study was to integrate these markers with a disease progression model and to identify their abnormal ranges.The data of 395 participants, including 86 normal subjects, 108 early mild cognitive impairment (EMCI) subjects, 120 late mild cognitive impairment (LMCI) subjects, and 81 AD subjects were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. For the participants, baseline and long-term data on cerebrospinal fluid Aβ42 and p-tau, hippocampal volume, and ADAS-cog were available. Various linear and nonlinear models were tested to determine the associations among the ratio of Aβ42 to p-tau (the Ratio), hippocampal volume and ADAS-cog.The most likely models for the Ratio, hippocampal volume, and ADAS-cog (logistic, Emax, and linear models, respectively) were used to construct the final model. Baseline disease state had an impact on all the 3 endpoints (the Ratio, hippocampal volume, and ADAS-cog), while APOEε4 genotype and age only influence the Ratio and hippocampal volume.The Ratio can be used to identify the disease stage for an individual, and clinical measures integrated with the Ratio improve the accuracy of mild cognitive impairment (MCI) to AD conversion forecasting." @default.
• W2068420983 created "2016-06-24" @default.
• W2068420983 creator A5035352293 @default.
• W2068420983 creator A5050475802 @default.
• W2068420983 creator A5059545505 @default.
• W2068420983 creator A5064564309 @default.
• W2068420983 creator A5081293290 @default.
• W2068420983 date "2014-08-04" @default.
• W2068420983 modified "2023-10-18" @default.
• W2068420983 title "Alzheimer's disease progression model based on integrated biomarkers and clinical measures" @default.
• W2068420983 cites W1969313677 @default.
• W2068420983 cites W1970684162 @default.
• W2068420983 cites W1980842500 @default.
• W2068420983 cites W1985747467 @default.
• W2068420983 cites W1992257573 @default.
• W2068420983 cites W2001253920 @default.
• W2068420983 cites W2006858320 @default.
• W2068420983 cites W2006905953 @default.
• W2068420983 cites W2013613063 @default.
• W2068420983 cites W2015675204 @default.
• W2068420983 cites W2036122182 @default.
• W2068420983 cites W2053684177 @default.
• W2068420983 cites W2054093987 @default.
• W2068420983 cites W2060240527 @default.
• W2068420983 cites W2061202562 @default.
• W2068420983 cites W2065535274 @default.
• W2068420983 cites W2066462635 @default.
• W2068420983 cites W2087167911 @default.
• W2068420983 cites W2096410114 @default.
• W2068420983 cites W2098176256 @default.
• W2068420983 cites W2129030910 @default.
• W2068420983 cites W2129497119 @default.
• W2068420983 cites W2131830246 @default.
• W2068420983 cites W2138545387 @default.
• W2068420983 cites W2155945712 @default.
• W2068420983 cites W2156024136 @default.
• W2068420983 cites W2164068160 @default.
• W2068420983 cites W2167840686 @default.
• W2068420983 doi "https://doi.org/10.1038/aps.2014.57" @default.
• W2068420983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4155529" @default.
• W2068420983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25088003" @default.
• W2068420983 hasPublicationYear "2014" @default.
• W2068420983 type Work @default.
• W2068420983 sameAs 2068420983 @default.
• W2068420983 citedByCount "16" @default.
• W2068420983 countsByYear W20684209832016 @default.
• W2068420983 countsByYear W20684209832017 @default.
• W2068420983 countsByYear W20684209832018 @default.
• W2068420983 countsByYear W20684209832019 @default.
• W2068420983 countsByYear W20684209832020 @default.
• W2068420983 countsByYear W20684209832021 @default.
• W2068420983 countsByYear W20684209832022 @default.
• W2068420983 countsByYear W20684209832023 @default.
• W2068420983 crossrefType "journal-article" @default.
• W2068420983 hasAuthorship W2068420983A5035352293 @default.
• W2068420983 hasAuthorship W2068420983A5050475802 @default.
• W2068420983 hasAuthorship W2068420983A5059545505 @default.
• W2068420983 hasAuthorship W2068420983A5064564309 @default.
• W2068420983 hasAuthorship W2068420983A5081293290 @default.
• W2068420983 hasBestOaLocation W20684209831 @default.
• W2068420983 hasConcept C126322002 @default.
• W2068420983 hasConcept C143998085 @default.
• W2068420983 hasConcept C148762608 @default.
• W2068420983 hasConcept C151956035 @default.
• W2068420983 hasConcept C15744967 @default.
• W2068420983 hasConcept C169760540 @default.
• W2068420983 hasConcept C169900460 @default.
• W2068420983 hasConcept C185711340 @default.
• W2068420983 hasConcept C2778373026 @default.
• W2068420983 hasConcept C2779134260 @default.
• W2068420983 hasConcept C2779483572 @default.
• W2068420983 hasConcept C2779651940 @default.
• W2068420983 hasConcept C502032728 @default.
• W2068420983 hasConcept C58693492 @default.
• W2068420983 hasConcept C71924100 @default.
• W2068420983 hasConceptScore W2068420983C126322002 @default.
• W2068420983 hasConceptScore W2068420983C143998085 @default.
• W2068420983 hasConceptScore W2068420983C148762608 @default.
• W2068420983 hasConceptScore W2068420983C151956035 @default.
• W2068420983 hasConceptScore W2068420983C15744967 @default.
• W2068420983 hasConceptScore W2068420983C169760540 @default.
• W2068420983 hasConceptScore W2068420983C169900460 @default.
• W2068420983 hasConceptScore W2068420983C185711340 @default.
• W2068420983 hasConceptScore W2068420983C2778373026 @default.
• W2068420983 hasConceptScore W2068420983C2779134260 @default.
• W2068420983 hasConceptScore W2068420983C2779483572 @default.
• W2068420983 hasConceptScore W2068420983C2779651940 @default.
• W2068420983 hasConceptScore W2068420983C502032728 @default.
• W2068420983 hasConceptScore W2068420983C58693492 @default.
• W2068420983 hasConceptScore W2068420983C71924100 @default.
• W2068420983 hasIssue "9" @default.
• W2068420983 hasLocation W20684209831 @default.
• W2068420983 hasLocation W20684209832 @default.
• W2068420983 hasLocation W20684209833 @default.
• W2068420983 hasLocation W20684209834 @default.
• W2068420983 hasOpenAccess W2068420983 @default.
• W2068420983 hasPrimaryLocation W20684209831 @default.
• W2068420983 hasRelatedWork W1525653175 @default.

• next