Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068431138> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2068431138 endingPage "397" @default.
- W2068431138 startingPage "385" @default.
- W2068431138 abstract "✓ Effects of intracarotid infusion of prostaglandins (PG) E 1 and F 2 a on the circulation to the dog brain were examined by fluorescein angiography, by measuring diameter changes in the epicerebral vessels, and by measuring microregional cerebral blood flow with 133 xenon and lithium-drift silicon detectors. PGE 1 at doses of 0.5 µg/min constricted the epicerebral arteries 700 µ or less in diameter, arrested fluorescein dye injected into the carotid system, and reduced rCBF by 42% with increase of collateral flow to the brain by the vertebrobasilar system. This effect was not obtained by PGE 1 to which 0.08% ethanol had been added. PGF 2 a at doses of 25 µg/min constricted epicerebral arterial vessels less than 200 µ in diameter, reduced rCBF by 35%, and decreased fluorescein dye in the cortical microcirculation with lengthening of the cerebral circulation time. Selective clipping of external and internal carotid arteries indicated that PGE 1 acts by constricting these vessels as well as the epicerebral arteries. Since prostaglandins are released from platelets as well as from stimulation of the cerebral cortex they should be considered as factors involved in the regulation of cerebral blood flow and in the mechanism of cerebral vasospasm. These properties of PGE 1 and PGF 2 a also imply the need for caution when these substances are used for clinical investigation." @default.
- W2068431138 created "2016-06-24" @default.
- W2068431138 creator A5010255118 @default.
- W2068431138 creator A5029261780 @default.
- W2068431138 creator A5035867025 @default.
- W2068431138 creator A5039457576 @default.
- W2068431138 creator A5055245274 @default.
- W2068431138 date "1972-10-01" @default.
- W2068431138 modified "2023-09-26" @default.
- W2068431138 title "Experimental vasoconstriction of cerebral arteries by prostaglandins" @default.
- W2068431138 cites W1900262093 @default.
- W2068431138 cites W1902192124 @default.
- W2068431138 cites W1965939927 @default.
- W2068431138 cites W1991751482 @default.
- W2068431138 cites W2008574207 @default.
- W2068431138 cites W2033248030 @default.
- W2068431138 cites W2034114627 @default.
- W2068431138 cites W2057836960 @default.
- W2068431138 cites W2060477495 @default.
- W2068431138 cites W2071233005 @default.
- W2068431138 cites W2082646452 @default.
- W2068431138 cites W2085717089 @default.
- W2068431138 cites W2090902242 @default.
- W2068431138 cites W2165771287 @default.
- W2068431138 cites W2312278566 @default.
- W2068431138 cites W2400727045 @default.
- W2068431138 cites W2472062592 @default.
- W2068431138 doi "https://doi.org/10.3171/jns.1972.37.4.0385" @default.
- W2068431138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5070868" @default.
- W2068431138 hasPublicationYear "1972" @default.
- W2068431138 type Work @default.
- W2068431138 sameAs 2068431138 @default.
- W2068431138 citedByCount "135" @default.
- W2068431138 countsByYear W20684311382013 @default.
- W2068431138 countsByYear W20684311382015 @default.
- W2068431138 countsByYear W20684311382020 @default.
- W2068431138 countsByYear W20684311382023 @default.
- W2068431138 crossrefType "journal-article" @default.
- W2068431138 hasAuthorship W2068431138A5010255118 @default.
- W2068431138 hasAuthorship W2068431138A5029261780 @default.
- W2068431138 hasAuthorship W2068431138A5035867025 @default.
- W2068431138 hasAuthorship W2068431138A5039457576 @default.
- W2068431138 hasAuthorship W2068431138A5055245274 @default.
- W2068431138 hasConcept C119671327 @default.
- W2068431138 hasConcept C126322002 @default.
- W2068431138 hasConcept C157767197 @default.
- W2068431138 hasConcept C158846371 @default.
- W2068431138 hasConcept C171614378 @default.
- W2068431138 hasConcept C2776820941 @default.
- W2068431138 hasConcept C2777736543 @default.
- W2068431138 hasConcept C2778506911 @default.
- W2068431138 hasConcept C2779961880 @default.
- W2068431138 hasConcept C2780662894 @default.
- W2068431138 hasConcept C42219234 @default.
- W2068431138 hasConcept C71924100 @default.
- W2068431138 hasConceptScore W2068431138C119671327 @default.
- W2068431138 hasConceptScore W2068431138C126322002 @default.
- W2068431138 hasConceptScore W2068431138C157767197 @default.
- W2068431138 hasConceptScore W2068431138C158846371 @default.
- W2068431138 hasConceptScore W2068431138C171614378 @default.
- W2068431138 hasConceptScore W2068431138C2776820941 @default.
- W2068431138 hasConceptScore W2068431138C2777736543 @default.
- W2068431138 hasConceptScore W2068431138C2778506911 @default.
- W2068431138 hasConceptScore W2068431138C2779961880 @default.
- W2068431138 hasConceptScore W2068431138C2780662894 @default.
- W2068431138 hasConceptScore W2068431138C42219234 @default.
- W2068431138 hasConceptScore W2068431138C71924100 @default.
- W2068431138 hasIssue "4" @default.
- W2068431138 hasLocation W20684311381 @default.
- W2068431138 hasLocation W20684311382 @default.
- W2068431138 hasOpenAccess W2068431138 @default.
- W2068431138 hasPrimaryLocation W20684311381 @default.
- W2068431138 hasRelatedWork W174245299 @default.
- W2068431138 hasRelatedWork W2068431138 @default.
- W2068431138 hasRelatedWork W2094101909 @default.
- W2068431138 hasRelatedWork W2118044332 @default.
- W2068431138 hasRelatedWork W2119521098 @default.
- W2068431138 hasRelatedWork W2134592756 @default.
- W2068431138 hasRelatedWork W2380163366 @default.
- W2068431138 hasRelatedWork W2550384086 @default.
- W2068431138 hasRelatedWork W2886600752 @default.
- W2068431138 hasRelatedWork W4310700289 @default.
- W2068431138 hasVolume "37" @default.
- W2068431138 isParatext "false" @default.
- W2068431138 isRetracted "false" @default.
- W2068431138 magId "2068431138" @default.
- W2068431138 workType "article" @default.