FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068431668> ?p ?o ?g. }

• W2068431668 endingPage "126" @default.
• W2068431668 startingPage "111" @default.
• W2068431668 abstract "To learn more about the pathophysiology of axonal injury and the significance of axon collaterals on the survival of axotomized cord-projection central neurons, we studied the survival rate, surrounding astrocytic and microglial reactions, and bouton coverage on rat rubrospinal cell bodies following their axonal lesion at the brain stem and upper cervical level. The brain stem lesion disconnected most rubrospinal neurons from all their targets, while the upper cervical lesion spared their supraspinal collaterals. Much higher cell loss accompanied by robust astrocytic and microglial reaction was found following brain stem than upper cervical lesion starting 4 days postaxotomy. The reaction of astrocytes had subsided while microglial reaction remained relatively robust by 10 weeks postaxotomy when the cell loss had slowed down. Ultrastructural observation revealed that reactive astrocytes covered 40%, an increase from the 20% of control, of brain stem-axotomized rubrospinal cell body surface at 4 days and 2 weeks and returned to normal levels by 10 weeks postlesion. An increase of apposition by axons and dendrites and a moderate decrease of round and flattened vesicle-containing bouton contacts at 4 days and 2 weeks and returning to normal levels at 10 weeks postaxotomy accompanied this. It appears that although axotomy induced robust astrocytic reaction around cord-projection central neurons, this, unlike their periphery-projection counterparts, failed to effectively strip their somatic synapses. In effect, this might in part determine neuronal fate following axonal injury." @default.
• W2068431668 created "2016-06-24" @default.
• W2068431668 creator A5031305567 @default.
• W2068431668 creator A5035897635 @default.
• W2068431668 creator A5050135440 @default.
• W2068431668 date "2003-01-01" @default.
• W2068431668 modified "2023-09-23" @default.
• W2068431668 title "Close Axonal Injury of Rubrospinal Neurons Induced Transient Perineuronal Astrocytic and Microglial Reaction That Coincided with Their Massive Degeneration" @default.
• W2068431668 cites W1497906567 @default.
• W2068431668 cites W1792452266 @default.
• W2068431668 cites W1971237450 @default.
• W2068431668 cites W1977591896 @default.
• W2068431668 cites W1978631802 @default.
• W2068431668 cites W1978685821 @default.
• W2068431668 cites W1990780029 @default.
• W2068431668 cites W1996327998 @default.
• W2068431668 cites W2008765010 @default.
• W2068431668 cites W2010247968 @default.
• W2068431668 cites W2011925126 @default.
• W2068431668 cites W2025472841 @default.
• W2068431668 cites W2030848480 @default.
• W2068431668 cites W2037839251 @default.
• W2068431668 cites W2040578268 @default.
• W2068431668 cites W2042466626 @default.
• W2068431668 cites W2053697917 @default.
• W2068431668 cites W2059714868 @default.
• W2068431668 cites W2064619205 @default.
• W2068431668 cites W2074938165 @default.
• W2068431668 cites W2082619657 @default.
• W2068431668 cites W2082806352 @default.
• W2068431668 cites W2084021257 @default.
• W2068431668 cites W2086148521 @default.
• W2068431668 cites W2088079706 @default.
• W2068431668 cites W2088786955 @default.
• W2068431668 cites W2092507916 @default.
• W2068431668 cites W2110401954 @default.
• W2068431668 cites W2114354962 @default.
• W2068431668 cites W2126706634 @default.
• W2068431668 cites W2147593622 @default.
• W2068431668 cites W2168483511 @default.
• W2068431668 cites W2235880247 @default.
• W2068431668 cites W2912016352 @default.
• W2068431668 cites W4244311268 @default.
• W2068431668 doi "https://doi.org/10.1006/exnr.2002.8057" @default.
• W2068431668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12504873" @default.
• W2068431668 hasPublicationYear "2003" @default.
• W2068431668 type Work @default.
• W2068431668 sameAs 2068431668 @default.
• W2068431668 citedByCount "14" @default.
• W2068431668 countsByYear W20684316682013 @default.
• W2068431668 countsByYear W20684316682014 @default.
• W2068431668 countsByYear W20684316682017 @default.
• W2068431668 countsByYear W20684316682018 @default.
• W2068431668 countsByYear W20684316682022 @default.
• W2068431668 crossrefType "journal-article" @default.
• W2068431668 hasAuthorship W2068431668A5031305567 @default.
• W2068431668 hasAuthorship W2068431668A5035897635 @default.
• W2068431668 hasAuthorship W2068431668A5050135440 @default.
• W2068431668 hasConcept C105702510 @default.
• W2068431668 hasConcept C142724271 @default.
• W2068431668 hasConcept C169760540 @default.
• W2068431668 hasConcept C203014093 @default.
• W2068431668 hasConcept C2776914184 @default.
• W2068431668 hasConcept C2779530196 @default.
• W2068431668 hasConcept C2779683492 @default.
• W2068431668 hasConcept C2779830541 @default.
• W2068431668 hasConcept C2780775167 @default.
• W2068431668 hasConcept C2781156865 @default.
• W2068431668 hasConcept C529278444 @default.
• W2068431668 hasConcept C71924100 @default.
• W2068431668 hasConcept C86803240 @default.
• W2068431668 hasConceptScore W2068431668C105702510 @default.
• W2068431668 hasConceptScore W2068431668C142724271 @default.
• W2068431668 hasConceptScore W2068431668C169760540 @default.
• W2068431668 hasConceptScore W2068431668C203014093 @default.
• W2068431668 hasConceptScore W2068431668C2776914184 @default.
• W2068431668 hasConceptScore W2068431668C2779530196 @default.
• W2068431668 hasConceptScore W2068431668C2779683492 @default.
• W2068431668 hasConceptScore W2068431668C2779830541 @default.
• W2068431668 hasConceptScore W2068431668C2780775167 @default.
• W2068431668 hasConceptScore W2068431668C2781156865 @default.
• W2068431668 hasConceptScore W2068431668C529278444 @default.
• W2068431668 hasConceptScore W2068431668C71924100 @default.
• W2068431668 hasConceptScore W2068431668C86803240 @default.
• W2068431668 hasIssue "1" @default.
• W2068431668 hasLocation W20684316681 @default.
• W2068431668 hasLocation W20684316682 @default.
• W2068431668 hasOpenAccess W2068431668 @default.
• W2068431668 hasPrimaryLocation W20684316681 @default.
• W2068431668 hasRelatedWork W1447085751 @default.
• W2068431668 hasRelatedWork W1967273876 @default.
• W2068431668 hasRelatedWork W2055919993 @default.
• W2068431668 hasRelatedWork W2128971541 @default.
• W2068431668 hasRelatedWork W2419116252 @default.
• W2068431668 hasRelatedWork W247987288 @default.
• W2068431668 hasRelatedWork W2791333980 @default.
• W2068431668 hasRelatedWork W2901041008 @default.
• W2068431668 hasRelatedWork W2996642893 @default.

• next