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- W2068434150 abstract "A comparison was made of the properties of collagen isolated from the skins of rats treated with sodium salicylate, hydrocortisone, chloroquine and phenylbutazone respectively, and from skins of lathyric rats treated during the development of lathyrism with these anti-rheumatic drugs. The rate of reconstitution of fibrils from acid soluble collagen isolated from the lathyric group is inhibited. The dissolution of the collagen gel formed on incubation at 37° after subsequent cooling to 5° is increased. These manifestations of lathyrus toxicity did not occur in rats given either sodium salicylate, phenylbutazone and chloroquine at the same time or the lathyrogen. Administration of hydrocortisone with the lathyrogen affected the lathyric properties of collagen to a lesser extent." @default.
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- W2068434150 date "1968-01-01" @default.
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- W2068434150 title "Effect of anti-rheumatic drugs on experimental lathyrism" @default.
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- W2068434150 doi "https://doi.org/10.1016/0006-2952(68)90159-7" @default.
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