FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068434913> ?p ?o ?g. }

• W2068434913 endingPage "1082" @default.
• W2068434913 startingPage "1075" @default.
• W2068434913 abstract "A pronase resistant 85-kd glycoprotein in the Concanavalin A-binding fraction (CABF) of biliary glycoproteins has been reported to act as a promotor of cholesterol crystallization. De Bruijn et al. (Gastroenterology 1996;110:1936-1944) found this protein in a low-density protein-lipid complex (LDP) with potent cholesterol crystallization promoting activity. This study identifies and characterizes this protein. An LDP was prepared from CABF by discontinuous gradient ultracentrifugation. Proteins were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), blotting and immunochemical staining with anti-carcinoembryonic antigen, CEA-related adhesion molecule 1 (CEACAM1) cross-reacting antibodies. Biliary concentrations of CEA cross-reacting proteins were determined in patients with and without gallstones. Two isoforms of CEACAM1 (85- and 115-kd bands), CEA and 2 CEA cross-reacting protein bands of 40 and 50 kd were found in human bile. All bands were also present in CABF, but only a subfraction of the 85-kd band found in the LDP was resistant to digestion with pronase. CEACAM1-85 exhibited potent cholesterol crystallization promoting activity in vitro and accounted for most of the activity in CABF. Total CEA cross-reacting protein concentrations were the same in gallbladder biles from patients with cholesterol and pigment gallstones but only half of those in biles from nongallstone subjects. In conclusion, we have identified the protein component of the cholesterol crystallization promoting LDP to be CEACAM1-85." @default.
• W2068434913 created "2016-06-24" @default.
• W2068434913 creator A5003115146 @default.
• W2068434913 creator A5018075590 @default.
• W2068434913 creator A5018165739 @default.
• W2068434913 creator A5024443935 @default.
• W2068434913 creator A5026281901 @default.
• W2068434913 creator A5029074725 @default.
• W2068434913 creator A5071399199 @default.
• W2068434913 creator A5086729574 @default.
• W2068434913 date "2001-12-01" @default.
• W2068434913 modified "2023-09-30" @default.
• W2068434913 title "Carcinoembryonic antigen-related cell adhesion molecule 1 is the 85-kilodalton pronase-resistant biliary glycoprotein in the cholesterol crystallization promoting low density protein-lipid complex" @default.
• W2068434913 cites W1583028644 @default.
• W2068434913 cites W1600097286 @default.
• W2068434913 cites W1602063632 @default.
• W2068434913 cites W1889798477 @default.
• W2068434913 cites W192535376 @default.
• W2068434913 cites W1968592882 @default.
• W2068434913 cites W1969242642 @default.
• W2068434913 cites W1973945079 @default.
• W2068434913 cites W1981345384 @default.
• W2068434913 cites W1985305423 @default.
• W2068434913 cites W1993641695 @default.
• W2068434913 cites W1999274658 @default.
• W2068434913 cites W2003503242 @default.
• W2068434913 cites W2006607634 @default.
• W2068434913 cites W2006986579 @default.
• W2068434913 cites W2019968787 @default.
• W2068434913 cites W2021740484 @default.
• W2068434913 cites W2022284603 @default.
• W2068434913 cites W2038134540 @default.
• W2068434913 cites W2052812233 @default.
• W2068434913 cites W2058352614 @default.
• W2068434913 cites W2066058356 @default.
• W2068434913 cites W2073581212 @default.
• W2068434913 cites W2075086418 @default.
• W2068434913 cites W2081818015 @default.
• W2068434913 cites W2085630676 @default.
• W2068434913 cites W2092439963 @default.
• W2068434913 cites W2107223965 @default.
• W2068434913 cites W2110661899 @default.
• W2068434913 cites W2123251101 @default.
• W2068434913 cites W2182140628 @default.
• W2068434913 cites W2187804863 @default.
• W2068434913 cites W2280885574 @default.
• W2068434913 cites W2340408129 @default.
• W2068434913 cites W2405153487 @default.
• W2068434913 cites W2412285723 @default.
• W2068434913 cites W2469942978 @default.
• W2068434913 cites W25447696 @default.
• W2068434913 cites W333096942 @default.
• W2068434913 doi "https://doi.org/10.1053/jhep.2001.29372" @default.
• W2068434913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11731994" @default.
• W2068434913 hasPublicationYear "2001" @default.
• W2068434913 type Work @default.
• W2068434913 sameAs 2068434913 @default.
• W2068434913 citedByCount "11" @default.
• W2068434913 countsByYear W20684349132012 @default.
• W2068434913 countsByYear W20684349132017 @default.
• W2068434913 countsByYear W20684349132021 @default.
• W2068434913 crossrefType "journal-article" @default.
• W2068434913 hasAuthorship W2068434913A5003115146 @default.
• W2068434913 hasAuthorship W2068434913A5018075590 @default.
• W2068434913 hasAuthorship W2068434913A5018165739 @default.
• W2068434913 hasAuthorship W2068434913A5024443935 @default.
• W2068434913 hasAuthorship W2068434913A5026281901 @default.
• W2068434913 hasAuthorship W2068434913A5029074725 @default.
• W2068434913 hasAuthorship W2068434913A5071399199 @default.
• W2068434913 hasAuthorship W2068434913A5086729574 @default.
• W2068434913 hasBestOaLocation W20684349131 @default.
• W2068434913 hasConcept C104317684 @default.
• W2068434913 hasConcept C108625454 @default.
• W2068434913 hasConcept C116084860 @default.
• W2068434913 hasConcept C121608353 @default.
• W2068434913 hasConcept C153911025 @default.
• W2068434913 hasConcept C181199279 @default.
• W2068434913 hasConcept C185592680 @default.
• W2068434913 hasConcept C19869320 @default.
• W2068434913 hasConcept C202751555 @default.
• W2068434913 hasConcept C2776708817 @default.
• W2068434913 hasConcept C2777387746 @default.
• W2068434913 hasConcept C2778163477 @default.
• W2068434913 hasConcept C2778913249 @default.
• W2068434913 hasConcept C2780340462 @default.
• W2068434913 hasConcept C54355233 @default.
• W2068434913 hasConcept C55493867 @default.
• W2068434913 hasConcept C71829478 @default.
• W2068434913 hasConcept C86803240 @default.
• W2068434913 hasConceptScore W2068434913C104317684 @default.
• W2068434913 hasConceptScore W2068434913C108625454 @default.
• W2068434913 hasConceptScore W2068434913C116084860 @default.
• W2068434913 hasConceptScore W2068434913C121608353 @default.
• W2068434913 hasConceptScore W2068434913C153911025 @default.
• W2068434913 hasConceptScore W2068434913C181199279 @default.
• W2068434913 hasConceptScore W2068434913C185592680 @default.
• W2068434913 hasConceptScore W2068434913C19869320 @default.
• W2068434913 hasConceptScore W2068434913C202751555 @default.

• next