Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068441377> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2068441377 endingPage "356" @default.
- W2068441377 startingPage "347" @default.
- W2068441377 abstract "The development of antiangiogenic drugs offers new promise in the treatment of malignancy. Suramin has been reported to inhibit tumor growth by blocking angiogenesis and has been used in clinical trials. The aim of the present study was to examine the effects of suramin on colonic anastomotic tumors in the rat.(a) Colonic anastomotic tumor was induced in 120 WAG/RIJ rats. Half of the animals were given 100 mg/kg of suramin intraperitoneally at the time of tumor induction. Rats were sacrificed after 2, 4 and 8 weeks; tumor take and tumor weight were evaluated. (b) The number of red blood cell clusters per x 400 field was counted in each tumor. (c) A lymphocyte transformation test was performed in four groups of animals, 2 weeks before and 2 weeks after tumor implantation and/or suramin administration.(a) A significant enhancement of tumor growth was observed in the suramin-treated animals. (b) This was accompanied by a significant increase in functional blood vessels. (c) Suramin-treated rats had markedly decreased lymphocyte stimulation, pointing to a possible immunosuppressive effect.The growth of an anastomotic colon tumor is rather enhanced by a single intraperitoneal administration of 100 mg/kg suramin in the rat, possibly by an unexpected immunosuppressive effect." @default.
- W2068441377 created "2016-06-24" @default.
- W2068441377 creator A5012298568 @default.
- W2068441377 creator A5013785233 @default.
- W2068441377 creator A5017684022 @default.
- W2068441377 creator A5024310088 @default.
- W2068441377 creator A5026761100 @default.
- W2068441377 creator A5029710716 @default.
- W2068441377 creator A5041256007 @default.
- W2068441377 creator A5043700021 @default.
- W2068441377 creator A5065583421 @default.
- W2068441377 creator A5076915126 @default.
- W2068441377 creator A5077849797 @default.
- W2068441377 date "1999-01-01" @default.
- W2068441377 modified "2023-09-23" @default.
- W2068441377 title "Effects of Suramin on Anastomotic Colon Tumors in a Rat Model" @default.
- W2068441377 cites W1974731323 @default.
- W2068441377 cites W1976963261 @default.
- W2068441377 cites W1981954986 @default.
- W2068441377 cites W2008736019 @default.
- W2068441377 cites W2012324487 @default.
- W2068441377 cites W2041555368 @default.
- W2068441377 cites W2042700683 @default.
- W2068441377 cites W2067997630 @default.
- W2068441377 cites W2068391435 @default.
- W2068441377 cites W2077933440 @default.
- W2068441377 cites W2088975276 @default.
- W2068441377 cites W2089294497 @default.
- W2068441377 cites W2124825512 @default.
- W2068441377 cites W2129415730 @default.
- W2068441377 cites W2133037916 @default.
- W2068441377 cites W2143604533 @default.
- W2068441377 cites W2155689571 @default.
- W2068441377 cites W2158743409 @default.
- W2068441377 cites W2282146109 @default.
- W2068441377 cites W2402476409 @default.
- W2068441377 cites W2405311118 @default.
- W2068441377 cites W2413076237 @default.
- W2068441377 doi "https://doi.org/10.1159/000008712" @default.
- W2068441377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10449994" @default.
- W2068441377 hasPublicationYear "1999" @default.
- W2068441377 type Work @default.
- W2068441377 sameAs 2068441377 @default.
- W2068441377 citedByCount "2" @default.
- W2068441377 crossrefType "journal-article" @default.
- W2068441377 hasAuthorship W2068441377A5012298568 @default.
- W2068441377 hasAuthorship W2068441377A5013785233 @default.
- W2068441377 hasAuthorship W2068441377A5017684022 @default.
- W2068441377 hasAuthorship W2068441377A5024310088 @default.
- W2068441377 hasAuthorship W2068441377A5026761100 @default.
- W2068441377 hasAuthorship W2068441377A5029710716 @default.
- W2068441377 hasAuthorship W2068441377A5041256007 @default.
- W2068441377 hasAuthorship W2068441377A5043700021 @default.
- W2068441377 hasAuthorship W2068441377A5065583421 @default.
- W2068441377 hasAuthorship W2068441377A5076915126 @default.
- W2068441377 hasAuthorship W2068441377A5077849797 @default.
- W2068441377 hasConcept C126322002 @default.
- W2068441377 hasConcept C170493617 @default.
- W2068441377 hasConcept C2776182878 @default.
- W2068441377 hasConcept C2780394083 @default.
- W2068441377 hasConcept C71924100 @default.
- W2068441377 hasConcept C98274493 @default.
- W2068441377 hasConceptScore W2068441377C126322002 @default.
- W2068441377 hasConceptScore W2068441377C170493617 @default.
- W2068441377 hasConceptScore W2068441377C2776182878 @default.
- W2068441377 hasConceptScore W2068441377C2780394083 @default.
- W2068441377 hasConceptScore W2068441377C71924100 @default.
- W2068441377 hasConceptScore W2068441377C98274493 @default.
- W2068441377 hasIssue "4" @default.
- W2068441377 hasLocation W20684413771 @default.
- W2068441377 hasLocation W20684413772 @default.
- W2068441377 hasOpenAccess W2068441377 @default.
- W2068441377 hasPrimaryLocation W20684413771 @default.
- W2068441377 hasRelatedWork W1557228442 @default.
- W2068441377 hasRelatedWork W1970786151 @default.
- W2068441377 hasRelatedWork W1983741994 @default.
- W2068441377 hasRelatedWork W2053382117 @default.
- W2068441377 hasRelatedWork W2057147067 @default.
- W2068441377 hasRelatedWork W2081439037 @default.
- W2068441377 hasRelatedWork W2114615326 @default.
- W2068441377 hasRelatedWork W2350570605 @default.
- W2068441377 hasRelatedWork W2750613276 @default.
- W2068441377 hasRelatedWork W2183852891 @default.
- W2068441377 hasVolume "31" @default.
- W2068441377 isParatext "false" @default.
- W2068441377 isRetracted "false" @default.
- W2068441377 magId "2068441377" @default.
- W2068441377 workType "article" @default.